Page last updated: 2024-09-03

sr 48692 and morphine

sr 48692 has been researched along with morphine in 2 studies

Compound Research Comparison

Studies
(sr 48692)
Trials
(sr 48692)
Recent Studies (post-2010)
(sr 48692)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
20333644,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomysr 48692 (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Craig, CR; Gully, D; Hawranko, AA; Monroe, PJ; Smith, DJ; Smith, DL; Smith, JP; Urban, MO1
Bredeloux, P; Costentin, J; Dubuc, I1

Other Studies

2 other study(ies) available for sr 48692 and morphine

ArticleYear
Dose-dependent pain-facilitatory and -inhibitory actions of neurotensin are revealed by SR 48692, a nonpeptide neurotensin antagonist: influence on the antinociceptive effect of morphine.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Male; Microinjections; Morphine; Neurotensin; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Sodium Chloride

1997
Interactions between NTS2 neurotensin and opioid receptors on two nociceptive responses assessed on the hot plate test in mice.
    Behavioural brain research, 2006, Dec-15, Volume: 175, Issue:2

    Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Histamine H1 Antagonists, Non-Sedating; Injections, Intraventricular; Ligands; Male; Mice; Morphine; Neurotensin; Pain Threshold; Piperidines; Pyrazoles; Quinolines; Reaction Time; Receptors, Neurotensin; Receptors, Opioid

2006