sch 34826 and naloxone
sch 34826 has been researched along with naloxone in 5 studies
Compound Research Comparison
| Studies (sch 34826) | Trials (sch 34826) | Recent Studies (post-2010) (sch 34826) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 31 | 2 | 0 | 20,134 | 1,257 | 3,321 |
Protein Interaction Comparison
| Protein | Taxonomy | sch 34826 (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bokszanska, A; Brinkman, EC; Cappendijk, SL; Dzoljic, M; Dzoljic, MR; Kaplan, CD; Korenhof, AM; Rupreht, J; Zijlstra, FJ | 1 |
| Herz, A; Parsons, CG | 1 |
| Barnett, A; Berger, JG; Billard, W; Chapman, R; Chipkin, RE; Iorio, LC | 1 |
| Innes, DG; Kavaliers, M | 1 |
| Kavaliers, M; Ossenkopp, KP; Prato, FS; Thomas, AW | 1 |
Other Studies
5 other study(ies) available for sch 34826 and naloxone
| Article | Year |
|---|---|
The effects of orally active enkephalinase inhibitors on morphine withdrawal syndrome.
Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dipeptides; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Morphine; Morphine Dependence; Naloxone; Neprilysin; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Thiorphan | 1992 |
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan | 1990 |
Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic.
Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dioxoles; Dipeptides; Drug Synergism; Enkephalin, Methionine; Gastrointestinal Motility; Male; Metalloendopeptidases; Mice; Naloxone; Neprilysin; Rats; Respiration | 1988 |
Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH 34826.
Topics: Analgesia; Analgesics; Animals; Dioxolanes; Dipeptides; Enkephalin, Leucine; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Peromyscus; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Restraint, Physical; Sex Characteristics; Stress, Psychological | 1993 |
Antinociceptive effects of a pulsed magnetic field in the land snail, Cepaea nemoralis.
Topics: Analgesia; Analgesics; Animals; Avoidance Learning; Dioxolanes; Dipeptides; Electric Stimulation; Magnetics; Microinjections; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Snails | 1997 |