Compounds > sch 34826
Page last updated: 2024-09-03

sch 34826 and naloxone

sch 34826 has been researched along with naloxone in 5 studies

Compound Research Comparison

Studies
(sch 34826)		Trials
(sch 34826)		Recent Studies (post-2010)
(sch 34826)		Studies
(naloxone)		Trials
(naloxone)		Recent Studies (post-2010) (naloxone)
312020,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomysch 34826 (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bokszanska, A; Brinkman, EC; Cappendijk, SL; Dzoljic, M; Dzoljic, MR; Kaplan, CD; Korenhof, AM; Rupreht, J; Zijlstra, FJ1
Herz, A; Parsons, CG1
Barnett, A; Berger, JG; Billard, W; Chapman, R; Chipkin, RE; Iorio, LC1
Innes, DG; Kavaliers, M1
Kavaliers, M; Ossenkopp, KP; Prato, FS; Thomas, AW1

Other Studies

5 other study(ies) available for sch 34826 and naloxone

ArticleYear
The effects of orally active enkephalinase inhibitors on morphine withdrawal syndrome.
    Neuroreport, 1992, Volume: 3, Issue:7

    Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dipeptides; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Morphine; Morphine Dependence; Naloxone; Neprilysin; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Thiorphan

1992
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan

1990
Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Administration, Oral; Analgesics; Animals; Dioxolanes; Dioxoles; Dipeptides; Drug Synergism; Enkephalin, Methionine; Gastrointestinal Motility; Male; Metalloendopeptidases; Mice; Naloxone; Neprilysin; Rats; Respiration

1988
Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH 34826.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:4

    Topics: Analgesia; Analgesics; Animals; Dioxolanes; Dipeptides; Enkephalin, Leucine; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Peromyscus; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Restraint, Physical; Sex Characteristics; Stress, Psychological

1993
Antinociceptive effects of a pulsed magnetic field in the land snail, Cepaea nemoralis.
    Neuroscience letters, 1997, Jan-31, Volume: 222, Issue:2

    Topics: Analgesia; Analgesics; Animals; Avoidance Learning; Dioxolanes; Dipeptides; Electric Stimulation; Magnetics; Microinjections; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Snails

1997