Page last updated: 2024-09-03

nnc 711 and naloxone

nnc 711 has been researched along with naloxone in 2 studies

Compound Research Comparison

Studies
(nnc 711)
Trials
(nnc 711)
Recent Studies (post-2010)
(nnc 711)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
11202120,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomynnc 711 (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fei, J; Guo, LH; Hu, JH; Jiang, J; Ma, YH; Mei, ZT; Yang, N; Zhang, XY; Zhou, XG1
Bagley, EE; Chefer, VI; Chieng, BC; Christie, MJ; Hacker, J; Mallet, C; McNally, GP; Perroud, J; Shippenberg, TS1

Other Studies

2 other study(ies) available for nnc 711 and naloxone

ArticleYear
Decrease of morphine-induced reward effects and withdrawal symptoms in mice overexpressing gamma-aminobutyric acid transporter I.
    Journal of neuroscience research, 2003, Nov-15, Volume: 74, Issue:4

    Topics: Adaptation, Physiological; Animals; Brain; Carrier Proteins; Conditioning, Psychological; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine Dependence; Naloxone; Narcotic Antagonists; Nipecotic Acids; Organic Anion Transporters; Oximes; Receptors, Opioid, mu; Reinforcement, Psychology; Substance Withdrawal Syndrome

2003
Drug-induced GABA transporter currents enhance GABA release to induce opioid withdrawal behaviors.
    Nature neuroscience, 2011, Oct-30, Volume: 14, Issue:12

    Topics: Analysis of Variance; Animals; Disease Models, Animal; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nipecotic Acids; Oximes; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors

2011