mosapride and naloxone
mosapride has been researched along with naloxone in 2 studies
Compound Research Comparison
| Studies (mosapride) | Trials (mosapride) | Recent Studies (post-2010) (mosapride) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 286 | 90 | 142 | 20,134 | 1,257 | 3,321 |
Protein Interaction Comparison
| Protein | Taxonomy | mosapride (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Geisslinger, G; Hummel, T; Lötsch, J; Schneider, A; Skarke, C | 1 |
| Horie, S; Kimura, H; Matsumoto, K; Tashima, K; Uchida, M | 1 |
Trials
1 trial(s) available for mosapride and naloxone
| Article | Year |
|---|---|
The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression.
Topics: Adult; Analgesics, Opioid; Animals; Benzamides; Carbon Dioxide; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Respiratory Insufficiency; Serotonin Receptor Agonists | 2005 |
Other Studies
1 other study(ies) available for mosapride and naloxone
| Article | Year |
|---|---|
Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Anti-Ulcer Agents; Antidiarrheals; Antiemetics; Benzamides; Benzyl Compounds; Breath Tests; Coloring Agents; Gastric Emptying; Loperamide; Male; Mice; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Phenolsulfonphthalein; Reproducibility of Results | 2008 |