mk 0663 has been researched along with morphine in 9 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | mk 0663 (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Boulet, J; Gottshall, S; Harrison, J; Mark, L; Pearson, M; Walker, K; Whiteside, GT | 1 |
| Chau-in, W; Prasertcharoensuk, W; Pulnitiporn, A; Sriraj, W; Tantanatewin, W; Thienthong, S | 1 |
| Conzen, P; Fleckenstein, J; Hatz, R; Heindl, B; Irnich, D; Kramer, S; Lang, PM; Lehmeyer, L; Mussack, T; Offenbächer, M; Plischke, H; Schober, G; Siebeck, M | 1 |
| Ko-iam, W; Paiboonworachat, S; Sandhu, T | 1 |
| Chen, L; Chitkara, DK; Curtis, SP; Mehta, A; Minkowitz, HS; Papanicolaou, DA; Peloso, PM; Rawal, N; Shah, S; Viscusi, E | 1 |
| Conzen, P; Czerner, S; Evtouchenko, E; Fleckenstein, J; Hatz, R; Heindl, B; Irnich, D; Kohls, N; Kramer, S; Lang, PM; Lehmeyer, L; Mussack, T; Rehm, M; Siebeck, M; Zwißler, B | 1 |
| Anastase, DM; Cionac Florescu, S; Munteanu, AM; Stoica, CI | 1 |
6 trial(s) available for mk 0663 and morphine
| Article | Year |
|---|---|
Prevention of post operative pain after abdominal hysterectomy by single dose etoricoxib.
Topics: Adult; Cyclooxygenase 2 Inhibitors; Etoricoxib; Female; Humans; Hysterectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Period; Pyridines; Sulfones | 2008 |
Etoricoxib--preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy--design and protocols.
Topics: Analgesia; Analgesia, Patient-Controlled; Analgesics; Aryl Hydrocarbon Hydroxylases; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 CYP2C19; Double-Blind Method; Drug Administration Schedule; Etoricoxib; Germany; Humans; Hyperalgesia; Laparotomy; Morphine; Narcotics; Pain Measurement; Pain Threshold; Pain, Postoperative; Placebo Effect; Polymorphism, Genetic; Pyridines; Research Design; Sulfones; Thoracotomy; Time Factors; Treatment Outcome | 2010 |
Effects of preemptive analgesia in laparoscopic cholecystectomy: a double-blind randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Diazepam; Double-Blind Method; Drug Therapy, Combination; Etoricoxib; Female; Headache; Humans; Length of Stay; Male; Middle Aged; Morphine; Narcotics; Pain Measurement; Pain, Postoperative; Postoperative Hemorrhage; Postoperative Nausea and Vomiting; Pyridines; Sulfones | 2011 |
Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Morphine; Narcotics; Pain, Postoperative; Pyridines; Sulfones | 2013 |
No effect of the cyclooxygenase-2 inhibitor etoricoxib on pre-emptive and post-operative analgesia in visceral surgery: results of a randomized controlled trial.
Topics: Abdomen; Adult; Aged; Analgesia; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Morphine; Narcotics; Pain Measurement; Pain Threshold; Pain, Postoperative; Pyridines; Sulfones | 2016 |
Is there any analgesic benefit from preoperative vs. postoperative administration of etoricoxib in total knee arthroplasty under spinal anaesthesia?: A randomised double-blind placebo-controlled trial.
Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Postoperative Care; Preoperative Care; Pyridines; Sulfones | 2016 |
3 other study(ies) available for mk 0663 and morphine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Pharmacological characterisation of a rat model of incisional pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Evaluation, Preclinical; Etoricoxib; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Indomethacin; Male; Morphine; Muscle, Skeletal; Naproxen; Nociceptors; Pain Threshold; Pain, Postoperative; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sulfonamides; Sulfones; Time Factors; Weight-Bearing | 2004 |