Page last updated: 2024-09-05

ly 353381 and afimoxifene

ly 353381 has been researched along with afimoxifene in 2 studies

Compound Research Comparison

Studies (ly 353381)	Trials (ly 353381)	Recent Studies (post-2010) (ly 353381)	Studies (afimoxifene)	Trials (afimoxifene)	Recent Studies (post-2010) (afimoxifene)
70	12	15	1,255	10	325

Protein Interaction Comparison

Protein	Taxonomy	afimoxifene (IC50)
Phospholipase D2	Homo sapiens (human)	6.5
Estrogen receptor	Homo sapiens (human)	0.0105
Estrogen-related receptor gamma	Homo sapiens (human)	0.0084
Phospholipase D1	Homo sapiens (human)	6.5
Estrogen receptor beta	Homo sapiens (human)	0.0102

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Diaugustine, RP; Hewitt, SC; Klotz, DM; Korach, KS	1
Bentrem, D; Dardes, RC; Jordan, VC; O'Regan, RM; Schafer, JM	1

Other Studies

2 other study(ies) available for ly 353381 and afimoxifene

Article	Year
Activation of a uterine insulin-like growth factor I signaling pathway by clinical and environmental estrogens: requirement of estrogen receptor-alpha. Endocrinology, 2000, Volume: 141, Issue:9 Topics: Animals; Benzhydryl Compounds; Blotting, Northern; Estradiol Congeners; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Estrogens, Non-Steroidal; Female; Insulin-Like Growth Factor I; Mice; Mice, Knockout; Mitosis; Ovariectomy; Phenols; Piperidines; Precipitin Tests; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Ribonucleases; RNA, Messenger; Signal Transduction; Tamoxifen; Thiophenes; Uterus	2000
Effects of the new selective estrogen receptor modulator LY353381.HCl (Arzoxifene) on human endometrial cancer growth in athymic mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12 Topics: Animals; Cell Division; Down-Regulation; Endometrial Neoplasms; Estrogen Antagonists; Female; Humans; Mice; Mice, Nude; Piperidines; Receptors, Estrogen; Tamoxifen; Thiophenes; Transplantation, Heterologous; Tumor Cells, Cultured	2001

Article

Year

Activation of a uterine insulin-like growth factor I signaling pathway by clinical and environmental estrogens: requirement of estrogen receptor-alpha.

Endocrinology, 2000, Volume: 141, Issue:9

Topics: Animals; Benzhydryl Compounds; Blotting, Northern; Estradiol Congeners; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Estrogens, Non-Steroidal; Female; Insulin-Like Growth Factor I; Mice; Mice, Knockout; Mitosis; Ovariectomy; Phenols; Piperidines; Precipitin Tests; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Ribonucleases; RNA, Messenger; Signal Transduction; Tamoxifen; Thiophenes; Uterus

2000

Effects of the new selective estrogen receptor modulator LY353381.HCl (Arzoxifene) on human endometrial cancer growth in athymic mice.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12

Topics: Animals; Cell Division; Down-Regulation; Endometrial Neoplasms; Estrogen Antagonists; Female; Humans; Mice; Mice, Nude; Piperidines; Receptors, Estrogen; Tamoxifen; Thiophenes; Transplantation, Heterologous; Tumor Cells, Cultured

2001