Page last updated: 2024-09-04

l 741742 and l 745870

l 741742 has been researched along with l 745870 in 3 studies

Compound Research Comparison

Studies
(l 741742)
Trials
(l 741742)
Recent Studies (post-2010)
(l 741742)
Studies
(l 745870)
Trials
(l 745870)
Recent Studies (post-2010) (l 745870)
100492029

Protein Interaction Comparison

ProteinTaxonomyl 741742 (IC50)l 745870 (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)9
D(4) dopamine receptorHomo sapiens (human)0.4785
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)9
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)9
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)9

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bristow, LJ; Hutson, PH; Rowley, M1
Hopkins, CR; Lindsley, CW1
Cao, BJ; Rodgers, RJ1

Reviews

2 review(s) available for l 741742 and l 745870

ArticleYear
Current and novel approaches to the drug treatment of schizophrenia.
    Journal of medicinal chemistry, 2001, Feb-15, Volume: 44, Issue:4

    Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists

2001
Return of D
    Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17

    Topics: Animals; Drug Discovery; Humans; Ligands; Molecular Targeted Therapy; Neoplasms; Parkinson Disease; Receptors, Dopamine D4; Small Molecule Libraries; Substance-Related Disorders

2017

Other Studies

1 other study(ies) available for l 741742 and l 745870

ArticleYear
Dopamine D4 receptor and anxiety: behavioural profiles of clozapine, L-745,870 and L-741,742 in the mouse plus-maze.
    European journal of pharmacology, 1997, Sep-24, Volume: 335, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Isoxazoles; Male; Maze Learning; Mice; Piperidines; Pyridines; Pyrroles; Receptors, Dopamine D4

1997