l 158809 and lisinopril
l 158809 has been researched along with lisinopril in 4 studies
Compound Research Comparison
| Studies (l 158809) | Trials (l 158809) | Recent Studies (post-2010) (l 158809) | Studies (lisinopril) | Trials (lisinopril) | Recent Studies (post-2010) (lisinopril) |
|---|---|---|---|---|---|
| 137 | 0 | 7 | 2,210 | 648 | 491 |
Protein Interaction Comparison
| Protein | Taxonomy | l 158809 (IC50) | lisinopril (IC50) |
|---|---|---|---|
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.0021 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.287 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0012 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.0012 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Patchett, AA | 1 |
| Bertani, T; Colosio, V; Corna, D; Donadelli, R; Facchinetti, D; Luzzana, E; Maffi, R; Remuzzi, G; Testa, D; Zoja, C | 1 |
| Benigni, A; Gagliardini, E; Grunkemeyer, JA; Kalluri, R; Remuzzi, G; Tomasoni, S; Zoja, C | 1 |
| Bos, H; De Boer, E; De Jong, PE; De Zeeuw, D; Henning, RH; Navis, G; Tiebosch, AT | 1 |
Other Studies
4 other study(ies) available for l 158809 and lisinopril
| Article | Year |
|---|---|
Excursions in drug discovery.
Topics: Awards and Prizes; Drug Design; Humans; Research; Technology, Pharmaceutical | 1993 |
The renoprotective properties of angiotensin-converting enzyme inhibitors in a chronic model of membranous nephropathy are solely due to the inhibition of angiotensin II: evidence based on comparative studies with a receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chronic Disease; Extracellular Matrix Proteins; Glomerular Filtration Rate; Glomerulonephritis, Membranous; Imidazoles; Kidney; Lisinopril; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Tetrazoles; Transforming Growth Factor beta | 1997 |
Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; DNA Primers; Glomerulonephritis; Imidazoles; In Situ Hybridization; Kidney Glomerulus; Lisinopril; Male; Membrane Proteins; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles | 2001 |
Addition of AT1 blocker fails to overcome resistance to ACE inhibition in adriamycin nephrosis.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Body Weight; Disease Models, Animal; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Imidazoles; Lisinopril; Male; Nephrosis; Proteinuria; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles | 2002 |