l 158809 and enalapril
l 158809 has been researched along with enalapril in 8 studies
Compound Research Comparison
| Studies (l 158809) | Trials (l 158809) | Recent Studies (post-2010) (l 158809) | Studies (enalapril) | Trials (enalapril) | Recent Studies (post-2010) (enalapril) |
|---|---|---|---|---|---|
| 137 | 0 | 7 | 6,311 | 1,924 | 859 |
Protein Interaction Comparison
| Protein | Taxonomy | l 158809 (IC50) | enalapril (IC50) |
|---|---|---|---|
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.3536 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 2.7083 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 1.2 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.14 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.14 |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fogo, A; Ichikawa, I; Kon, V | 1 |
| Fogo, A; Freeman, M; Lo, W; Oikawa, T; Vaughan, DE | 1 |
| Fukui, M; Sekizuka, K; Shirato, I; Shou, I; Suzuki, S; Tomino, Y; Wang, LN; Yamamoto, M | 1 |
| Hori, M; Hoshida, S; Kuzuya, T; Yamashita, N | 1 |
| Gerdes, AM; Harris, J; Lu, W; Said, S; Tamura, T | 1 |
| Cohen, EP; Fish, BL; Molteni, A; Moulder, JE; Taylor, JM; Veno, PA; Ward, WF; Wolfe, LF | 1 |
| Coppey, LJ; Davidson, EP; Gellett, JS; Lund, DD; Oltman, CL; Rinehart, TW; Yorek, MA | 1 |
| Brooks, RM; Faraci, FM; Heistad, DD; Lund, DD | 1 |
Other Studies
8 other study(ies) available for l 158809 and enalapril
| Article | Year |
|---|---|
Bradykinin causes selective efferent arteriolar dilation during angiotensin I converting enzyme inhibition.
Topics: Angiotensin Receptor Antagonists; Animals; Arterioles; Bradykinin; Bradykinin Receptor Antagonists; Enalapril; Furosemide; Imidazoles; Male; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles; Vasodilation; Water Deprivation | 1993 |
Modulation of plasminogen activator inhibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cytokines; Enalapril; Fibrin; Fibrinolysin; Fibrosis; Gene Expression Regulation, Enzymologic; Growth Substances; Imidazoles; In Situ Hybridization; Kidney; Male; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; RNA, Messenger; Tetrazoles; Thrombosis; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; Vasoconstrictor Agents | 1997 |
Effects of treatment with angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor antagonist (AIIRA) on renal function and glomerular injury in subtotal nephrectomized rats.
Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Creatinine; Enalapril; Glomerulonephritis; Hydralazine; Hydrochlorothiazide; Imidazoles; Kidney; Kidney Glomerulus; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Reserpine; Tetrazoles | 1997 |
Differential effects of long-term renin-angiotensin system blockade on limitation of infarct size in cholesterol-fed rabbits.
Topics: Analysis of Variance; Animals; Cholesterol, Dietary; Disease Models, Animal; Enalapril; Endothelium, Vascular; Hemodynamics; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion; Probability; Rabbits; Reference Values; Renin-Angiotensin System; Survival Rate; Tetrazoles | 2000 |
Reverse remodeling of cardiac myocyte hypertrophy in hypertension and failure by targeting of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Echocardiography; Enalapril; Female; Heart Failure; Hypertension, Renal; Imidazoles; Muscle Fibers, Skeletal; Myocardium; Organ Size; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling | 2000 |
Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bone Marrow Transplantation; Captopril; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Fibrosis; Imidazoles; Kidney Diseases; Male; Radiotherapy; Rats; Tetrazoles; Time Factors | 2001 |
ACE inhibitor or angiotensin II receptor antagonist attenuates diabetic neuropathy in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combination; Enalapril; Imidazoles; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tetrazoles | 2006 |
Role of angiotensin II in endothelial dysfunction induced by lipopolysaccharide in mice.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Endotoxemia; Imidazoles; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitroprusside; Oxidative Stress; Renin-Angiotensin System; Superoxides; Tetrazoles; Vasodilation; Vasodilator Agents | 2007 |