eglumetad and morphine
eglumetad has been researched along with morphine in 5 studies
Compound Research Comparison
| Studies (eglumetad) | Trials (eglumetad) | Recent Studies (post-2010) (eglumetad) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 190 | 5 | 48 | 44,270 | 5,200 | 8,695 |
Protein Interaction Comparison
| Protein | Taxonomy | eglumetad (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Rasmussen, K; Vandergriff, J | 1 |
| Brański, P; Chojnacka-Wójcik, E; Kłodzińska, A; Pałucha, A; Pilc, A; Popik, P | 1 |
| Kozela, E; Pilc, A; Popik, P | 1 |
| Klein, S; Nicolas, LB; Prinssen, EP | 1 |
| Filarowska, J; Gawel, K; Gibula-Bruzda, E; Jenda-Wojtanowska, M; Kedzierska, E; Komsta, L; Kotlinska, JH; Marszalek-Grabska, M; Talarek, S; Wojtanowski, KK | 1 |
Other Studies
5 other study(ies) available for eglumetad and morphine
| Article | Year |
|---|---|
The selective mGlu2/3 receptor agonist LY354740 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Electrophysiology; Excitatory Amino Acid Agonists; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Dependence; Naltrexone; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substance Withdrawal Syndrome | 1999 |
Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bridged Bicyclo Compounds; Conflict, Psychological; Drinking; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Narcotics; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Substance Withdrawal Syndrome | 1999 |
Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; Male; Memantine; Mice; Morphine; Pain; Pain Measurement; Receptors, Metabotropic Glutamate | 2000 |
Defensive-like behaviors induced by ultrasound: further pharmacological characterization in Lister-hooded rats.
Topics: Amines; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Buspirone; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diazepam; Dose-Response Relationship, Drug; Escape Reaction; Fear; Freezing Reaction, Cataleptic; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Imidazoles; Male; Morphine; Motor Activity; Nociceptin Receptor; Pregabalin; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Opioid; Spiro Compounds; Thiazoles; Ultrasonics | 2007 |
The influence of AMN082, metabotropic glutamate receptor 7 (mGlu7) allosteric agonist on the acute and chronic antinociceptive effects of morphine in the tail-immersion test in mice: Comparison with mGlu5 and mGlu2/3 ligands.
Topics: Allosteric Regulation; Analgesics; Animals; Benzhydryl Compounds; Bridged Bicyclo Compounds; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Nociceptive Pain; Pyridines; Pyridones; Random Allocation; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tail; Thiazoles | 2018 |