biotin and irinotecan
biotin has been researched along with irinotecan in 4 studies
Compound Research Comparison
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (irinotecan) | Trials (irinotecan) | Recent Studies (post-2010) (irinotecan) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 8,002 | 1,885 | 3,752 |
Protein Interaction Comparison
| Protein | Taxonomy | biotin (IC50) | irinotecan (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 2.7 | |
| Interstitial collagenase | Homo sapiens (human) | 6.06 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.556 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 3.171 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.827 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 7.9 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 4.7667 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Amessou, M; Decaudin, D; El Alaoui, A; Florent, JC; Johannes, L; Sarr, M; Schmidt, F | 1 |
| Amini, M; Atyabi, F; Baharian, A; Dinarvand, R; Ghahremani, MH; Gharghabi, M; Mehdizadeh, M; Ostad, SN; Rouhani, H; Sepehri, N; Varshochian, R | 1 |
| Chen, Y; Dai, Y; Ye, T; Zhang, Y | 1 |
Other Studies
4 other study(ies) available for biotin and irinotecan
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; HT29 Cells; Humans; Irinotecan; Prodrugs; Shiga Toxin; Shiga Toxins; Topoisomerase II Inhibitors; Trihexosylceramides | 2007 |
Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Biotin; Camptothecin; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hydrogen-Ion Concentration; Irinotecan; Kinetics; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; Cell Line, Tumor; Fibroblasts; HeLa Cells; Humans; Irinotecan; Mice; NIH 3T3 Cells; Valproic Acid | 2023 |