Page last updated: 2024-09-05

biotin and irinotecan

biotin has been researched along with irinotecan in 4 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(irinotecan)
Trials
(irinotecan)
Recent Studies (post-2010) (irinotecan)
14,847953,8828,0021,8853,752

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)irinotecan (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.7
Interstitial collagenaseHomo sapiens (human)6.06
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.556
Alpha-2C adrenergic receptorHomo sapiens (human)3.171
AcetylcholinesteraseHomo sapiens (human)1.827
Multidrug and toxin extrusion protein 2Homo sapiens (human)7.9
Multidrug and toxin extrusion protein 1Homo sapiens (human)4.7667

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Amessou, M; Decaudin, D; El Alaoui, A; Florent, JC; Johannes, L; Sarr, M; Schmidt, F1
Amini, M; Atyabi, F; Baharian, A; Dinarvand, R; Ghahremani, MH; Gharghabi, M; Mehdizadeh, M; Ostad, SN; Rouhani, H; Sepehri, N; Varshochian, R1
Chen, Y; Dai, Y; Ye, T; Zhang, Y1

Other Studies

4 other study(ies) available for biotin and irinotecan

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:34

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; HT29 Cells; Humans; Irinotecan; Prodrugs; Shiga Toxin; Shiga Toxins; Topoisomerase II Inhibitors; Trihexosylceramides

2007
Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy.
    Artificial cells, nanomedicine, and biotechnology, 2017, Volume: 45, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Biotin; Camptothecin; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hydrogen-Ion Concentration; Irinotecan; Kinetics; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2017
Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates.
    Molecules (Basel, Switzerland), 2023, May-07, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; Cell Line, Tumor; Fibroblasts; HeLa Cells; Humans; Irinotecan; Mice; NIH 3T3 Cells; Valproic Acid

2023