ae0047 has been researched along with nicardipine in 6 studies
| Studies (ae0047) | Trials (ae0047) | Recent Studies (post-2010) (ae0047) | Studies (nicardipine) | Trials (nicardipine) | Recent Studies (post-2010) (nicardipine) |
|---|---|---|---|---|---|
| 23 | 0 | 1 | 2,646 | 444 | 312 |
| Protein | Taxonomy | ae0047 (IC50) | nicardipine (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8.314 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 8 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 4.2992 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.42 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1.69 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 2.5 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 1.69 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 4.925 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishikawa, M; Okamura, T; Toda, N; Yoshida, K | 1 |
| Hayashi, K; Kido, H; Shinyama, H; Uchida, T; Watanabe, M | 1 |
| Ebisu, H; Egi, Y; Fujino, Y; Hayashi, K; Inoue, S; Kido, H; Kubo, Y; Nakamura, N; Nishikawa, M; Ohtaki, Y; Uchida, T; Yamanaga, K | 1 |
| Kagitani, Y; Kawamura, T; Nagai, H; Nakamura, N; Narita, Y; Shinyama, H | 1 |
| Gohda, M; Kido, H; Matzno, S; Nakamura, N; Nishikawa, M; Shinyama, H; Yamanaga, K | 1 |
| Hayashi, K; Matsumura, Y; Ohmagari, M; Tamai, I; Yamasaki, T | 1 |
6 other study(ies) available for ae0047 and nicardipine
| Article | Year |
|---|---|
AE0047, a new dihydropyridine Ca2+ entry blocker, inhibits the responses to adrenergic nerve stimulation and substance P in dog mesenteric arteries.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Mesenteric Arteries; Nicardipine; Substance P; Sympathetic Nervous System; Tritium; Vasodilation | 1992 |
Effects of AE0047 on renal haemodynamics and function in anaesthetized dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Dogs; Hemodynamics; Infusions, Intra-Arterial; Injections, Intravenous; Kidney; Natriuresis; Nicardipine; Renal Artery | 1993 |
[Antihypertensive effects of a novel calcium antagonist, AE0047, in various hypertensive models].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypertension, Renal; Injections, Intravenous; Nicardipine; Nitrendipine; Rats; Rats, Inbred SHR | 1997 |
Therapeutic effects of AE0047, a novel calcium antagonist, on progression of brain damage after stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Brain; Calcium Channel Blockers; Cerebrovascular Disorders; Dihydropyridines; Hydralazine; Male; Nicardipine; Rats; Rats, Inbred SHR; Vasodilator Agents | 1998 |
Calcium channel blocking and vasodilating actions of the novel dihydropyridine derivative AE0047.
Topics: Animals; Antihypertensive Agents; Aorta; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Cattle; Dihydropyridines; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Nicardipine; Nitrendipine; Patch-Clamp Techniques; Rats; Structure-Activity Relationship; Vasodilator Agents | 1998 |
Inhibitory effects of AE0047, a new dihydropyridine Ca(2+) channel blocker, on renal nerve stimulation-induced renal actions in anesthetized dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Electric Stimulation; Female; Infusions, Intra-Arterial; Kidney; Male; Nicardipine; Renal Circulation | 2000 |