Page last updated: 2024-09-27

Merycism

A gastrointestinal disorder characterized by repetitive and effortless regurgitation of ingested food from the stomach to the oral cavity in the early POSTPRANDIAL PERIOD. It is associated with functional gastrointestinal pathology (e.g., increased intra-gastric pressure) and psychiatric disorders (e.g., anxiety, depression). It is not limited to infants and distinct from GERD and VOMITING.

Synonyms(3)

Synonym
Rumination Disorders
Rumination Syndrome
Merycism

Research Excerpts

Overview

ExcerptReference
"Rumination syndrome is a functional disorder characterized by the involuntary regurgitation of recently swallowed food from the stomach into the mouth, from where it can be re-chewed or expelled."( Alcala-Gonzalez, LG; Barba, E; Serra, X, 2022)

Research

Studies (5)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's0 (0.00)28.8240
2020's5 (100.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
baclofen0low20
pica0low30

Protein Targets (40)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
thioredoxin reductase1001
phosphopantetheinyl transferase1001
ATAD5 protein, partial1001
NFKB1 protein, partial1001
GLI family zinc finger 31001
AR protein1001
regulator of G-protein signaling 41001
67.9K protein1001
euchromatic histone-lysine N-methyltransferase 21001
activating transcription factor 61001
Bloom syndrome protein isoform 11001
D(1A) dopamine receptor1001
cytochrome P450 3A4 isoform 11001
histone acetyltransferase KAT2A isoform 11001
lamin isoform A-delta101001
Gamma-aminobutyric acid receptor subunit pi1001
ATP-binding cassette sub-family C member 30101
Multidrug resistance-associated protein 40101
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Bile salt export pump0101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21012
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Gamma-aminobutyric acid receptor subunit alpha-11012
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21012
GABA theta subunit1001
Canalicular multispecific organic anion transporter 10101
Gamma-aminobutyric acid receptor subunit epsilon1001
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
ATP-dependent phosphofructokinase1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]