serotonin adipinate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

serotonin adipinate: prevents postoperative intestinal paresis; RN given refers to (1:1) mixture [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	202856
MeSH ID	M0166516

Synonyms (25)

Synonym
5-hydroxytryptamine adipate
serotonin adipinate
H-8050
5-hydroxytryptamine, adipate salt
3-(2-aminoethyl)-1h-indol-5-ol; hexanedioic acid
13425-34-8
16031-83-7
hexanedioic acid - 3-(2-aminoethyl)-1h-indol-5-ol (1:1)
STL372658
3-(2-aminoethyl)-1h-indol-5-ol adipate
AKOS022181909
BBL029161
3-(2-aminoethyl)-5-hydroxyindole adipate salt
hydroxytryptamine,adipate salt
F13491
VS-09132
3-(2-aminoethyl)-5-hydroxyindole adipate
DTXSID80928536
hexanedioic acid--3-(2-aminoethyl)-1h-indol-5-ol (1/1)
3-(2-aminoethyl)-1h-indol-5-ol;hexanedioic acid
FT-0774636
5-hydroxytryptamine adipic acid salt
1h-indol-5-ol, 3-(2-aminoethyl)-, hexanedioate (1:1)
serotonin adipate [who-dd]
indol-5-ol, 3-(2-aminoethyl)-, adipate (1:1)

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (8.33)	18.7374
1990's	4 (33.33)	18.2507
2000's	6 (50.00)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	11.72 (24.57)
Research Supply Index	3.18 (2.92)
Research Growth Index	4.90 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (11.72)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	3 (15.00%)	5.53%
Reviews	3 (15.00%)	6.00%
Case Studies	1 (5.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	13 (65.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
histamine [no description available]	2.4	2	0	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter

Condition	Relationship Strength	Studies	Trials
Chronic Idiopathic Intestinal Pseudo-Obstruction [description not available]	4.71	2	1
Complication, Postoperative [description not available]	5.47	3	1
Intestinal Pseudo-Obstruction A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.	4.71	2	1
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	5.47	3	1
Heart Disease, Ischemic [description not available]	3.33	2	0
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	2.92	1	0
Myocardial Ischemia A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).	3.33	2	0
Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.	3.4	1	1
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	3.4	1	1
Intestinal Obstruction Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.	2.91	1	0
Arterial Obstructive Diseases [description not available]	1.99	1	0
Diabetic Angiopathies VASCULAR DISEASES that are associated with DIABETES MELLITUS.	1.99	1	0
Arterial Occlusive Diseases Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.	1.99	1	0
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2	1	0
Gastroduodenal Ulcer [description not available]	2	1	0
Peptic Ulcer Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).	2	1	0
Gastric Ulcer [description not available]	2	1	0
Stomach Ulcer Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).	2	1	0
Cardiomyopathies, Primary [description not available]	2.01	1	0
Cardiomyopathies A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).	2.01	1	0
Primary Peritonitis [description not available]	3.36	1	1
Peritonitis INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.	3.36	1	1

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