| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
azacitidine
Azacitidine: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.. 5-azacytidine : An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia. | 3.25 | 1 | 0 | N-glycosyl-1,3,5-triazine;
nucleoside analogue | antineoplastic agent |
lenthionine
lenthionine: isolated from the Shiitake mushroom Lenthinus edodes | 3.25 | 1 | 0 | pentathiepane | |
eudistomin e
eudistomin E: structure known; isolated from the marine tunicate Eudistoma album | 3.25 | 1 | 0 | | |
oxadiazoles
Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms. | 4.58 | 7 | 0 | | |
essramycin
essramycin: from the culture broth of the marine Streptomyces; structure in first source | 3.25 | 1 | 0 | triazolopyrimidines | metabolite |
phidianidine a
phidianidine A: antineoplastic from the marine opisthobranch mollusk Phidiana militaris; structure in first source | 4.96 | 6 | 0 | | |
guanosine 5'-o-(3-thiotriphosphate)
Guanosine 5'-O-(3-Thiotriphosphate): Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes. | 2.07 | 1 | 0 | nucleoside triphosphate analogue | |
concanavalin a
Concanavalin A: A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures. | 2.17 | 1 | 0 | | |