Page last updated: 2024-11-05
n-amyl butyrate
Description
n-Amyl butyrate is an ester with a fruity, apple-like odor. It is used in the fragrance industry as a flavoring agent and as a component in artificial fruit flavors. The compound is synthesized by reacting n-amyl alcohol with butyric acid in the presence of a catalyst. n-Amyl butyrate is also found naturally in some fruits, such as apples and pears. Research has shown that n-amyl butyrate has potential antimicrobial activity against certain bacteria and fungi. This activity has led to interest in exploring its potential as a food preservative or as a component in topical antimicrobial agents. Studies are also exploring the effects of n-amyl butyrate on insect behavior and its potential use as a biopesticide. This compound is also being investigated for its potential effects on human health, including its potential to modulate the immune system.'
pentyl butyrate : The butyrate ester of pentan-1-ol. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 10890 |
| CHEMBL ID | 3183048 |
| CHEBI ID | 87684 |
| SCHEMBL ID | 117196 |
| MeSH ID | M0134423 |
Synonyms (51)
| Synonym |
|---|
| 3q2jp0vd8j , |
| unii-3q2jp0vd8j |
| 1-pentyl butyrate |
| wln: 5ov3 |
| pentyl butanoate |
| n-pentyl butanoate |
| butanoic acid, pentyl ester |
| pentyl butyrate |
| amyl butyrate |
| nsc7935 |
| n-amyl butyrate |
| nsc-7935 |
| n-pentyl n-butyrate |
| 540-18-1 |
| butyric acid, pentyl ester |
| fema no. 2059 |
| amyl butyrate (natural) |
| ai3-06124 |
| nsc 7935 |
| einecs 208-739-2 |
| brn 1752307 |
| n-pentyl butyrate |
| amyl butanoate |
| inchi=1/c9h18o2/c1-3-5-6-8-11-9(10)7-4-2/h3-8h2,1-2h |
| amyl butyrate, >=98%, fg |
| butyric acid amyl ester |
| B0755 |
| dtxsid4041604 , |
| NCGC00255424-01 |
| tox21_302013 |
| cas-540-18-1 |
| dtxcid2021604 |
| FT-0686709 |
| AKOS015903371 |
| SCHEMBL117196 |
| amyl butyrate [fcc] |
| amyl butyrate [fhfi] |
| n-amyl butyrate [mi] |
| butanoic acid pentyl ester |
| CFNJLPHOBMVMNS-UHFFFAOYSA-N |
| n-amyl n-butyrate |
| chebi:87684 , |
| CHEMBL3183048 |
| LMFA07010989 |
| mfcd00048850 |
| n-butyric acid n-amyl ester |
| amylbutyrat |
| pentyl butanoate, 9ci |
| n-amyl butyrate, 8ci |
| fema 2059 |
| Q419484 |
Roles (1)
| Role | Description |
|---|
| metabolite | Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
| Class | Description |
|---|
| butyrate ester | Any carboxylic ester where the carboxylic acid component is butyric acid. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein Targets (6)
Potency Measurements
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 17.45
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 17.45 (24.57) | | Research Supply Index | 2.20 (2.92) | | Research Growth Index | 4.46 (4.65) | | Search Engine Demand Index | 10.37 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (12.50%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (87.50%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |