laurinterol and Breast-Neoplasms

Macroalgae represent an important source of bioactive compounds with a wide range of biotechnological applications. Overall, the discovery of effective cytotoxic compounds with pharmaceutical potential is a significant challenge, mostly because they are scarce in nature or their total synthesis is not efficient, while the bioprospecting models currently used do not predict clinical responses. Given this context, we used three-dimensional (3D) cultures of human breast cancer explants to evaluate the antitumoral effect of laurinterol, the major compound of an ethanolic extract of

Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cells, Cultured; Chlorocebus aethiops; Female; Humans; Laurencia; MCF-7 Cells; Sesquiterpenes; Vero Cells