Compounds > fervenulin
Page last updated: 2024-11-08

fervenulin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fervenulin: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID249646
SCHEMBL ID2264237
MeSH IDM0051071

Synonyms (45)

Synonym
HMS1691K15
pyrimido(5,4-e)-as-triazine-5,7(6h,8h)-dione, 6,8-dimethyl-
nsc 68158
10204-bii
6,8-dimethylpyrimido(5,4-e)-as-triazine-5,7(6h,8h)dione
6,8-dimethylpyrimido(5,4-e)-as-triazine-5,7(6h,8h)-dione
pyrimido(5,4-e)-1,2,4-triazine-5,7(6h,8h)-dione, 6,8-dimethyl-
ai3-50812
compound 7215
nsc-68158
pyrimido[5,2,4-triazine-5,7(6h,8h)-dione, 6,8-dimethyl-
6,4-e]-as-triazine-5,7(6h,8h)-dione
fh-3582-a
u-7118
pyrimido[5,7(6h,8h)-dione, 6,8-dimethyl-
fervenulin
kc 1017
6,8-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
planomycin
NSC68158 ,
6,8-dimethyl-8h-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
483-57-8
fervenuline
STK177196
6,8-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(6h,8h)-dione
AKOS000714962
CCG-16573
unii-1lvq80w0bm
1lvq80w0bm ,
102646-55-9
pulanomycin
6,8-dimethylpyrimido(5,4-e)-1,2,4-triazine-5,7-(6h,8h)-dione
u 7118
fervenulin [mi]
SCHEMBL2264237
pulanomycin (salt/mix)
6,8-dimethylpyrimido[5,4-e]-1,2,4-triazine-5,7(6h,8h)-dione
RRTKVYSLIGQWCO-UHFFFAOYSA-N
antibiotic 10204-bii;10204-bii; planomycin; kc 1017
BCP31998
Q27252587
HY-121325
CS-0081443
6,8-dimethyl-5h,6h,7h,8h-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
DTXSID601032309
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.61 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
toxoflavin
toxoflavin: azapteridine antibiotic; structure. toxoflavin : A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7.		2.9340carbonyl compound;
pyrimidotriazine		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
toxin;
virulence factor;
Wnt signalling inhibitor
reumycin
reumycin: isolated from Actinomyces; structure. reumycin : A pyrimidotriazine that is 6-methyl-5,6,7,8-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 6.		7.4120carbonyl compound;
pyrimidotriazine		antimicrobial agent;
antineoplastic agent;
bacterial metabolite
pyrimidinones
Pyrimidinones: Heterocyclic compounds known as 2-pyrimidones (or 2-hydroxypyrimidines) and 4-pyrimidones (or 4-hydroxypyrimidines) with the general formula C4H4N2O.		2.9340
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio
[description not available]		02.0610
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)		02.0610