calcium silicate profile

Calcium silicate is a general term for a family of inorganic compounds composed of calcium oxide (CaO) and silica (SiO2). They are typically synthesized by reacting calcium hydroxide (Ca(OH)2) with silica in a high-temperature process. Calcium silicates exhibit diverse properties depending on their specific composition and structure. Some common forms include:

- **Wolllastonite (CaSiO3):** A naturally occurring mineral with high thermal stability, often used in ceramics and glass production.

- **Xonotlite (Ca6Si6O17(OH)2):** Known for its high tensile strength, used in cement and construction materials.

- **Tricalcium silicate (Ca3SiO5):** A major component of Portland cement, responsible for early strength development.

- **Dicalcium silicate (Ca2SiO4):** Another component of Portland cement, contributing to long-term strength.

Calcium silicates find applications in various industries:

- **Building and construction:** Used in cement, concrete, mortar, and insulation.
- **Ceramics and glass:** Employed in the manufacturing of tiles, bricks, and glass products.
- **Agriculture:** Used as a soil amendment to improve drainage and nutrient availability.
- **Medicine:** Some calcium silicates have been explored for drug delivery and wound healing applications.

Extensive research on calcium silicates focuses on areas like:

- **Synthesis and characterization:** Developing novel synthesis methods and understanding their structure-property relationships.
- **Performance optimization:** Improving their strength, durability, and resistance to degradation.
- **Environmental applications:** Exploring their potential for sequestering pollutants and remediating contaminated soil and water.
- **Biocompatibility and bioactivity:** Investigating their potential in biomedical applications, such as bone regeneration.

Overall, calcium silicates are versatile materials with a wide range of applications and continue to be studied for their potential in various technological advancements.'

ID Source	ID
PubMed CID	14941
MeSH ID	M0098430

Synonym
ec 215-710-8
nsc 57629
calcium silicate [nf]
unii-s4255p4g5m
s4255p4g5m ,
calcium silicate (nf)
D03309
1344-95-2
marimet 45
hsdb 705
einecs 215-710-8
silene ef
florite r
silicic acid, calcium salt
microcal et
calflo e
calcium monosilicate
microcal 160
micro-cel b
sw 400
micro-cel e
cs lafarge
calcium silicate, synthetic nonfibrous
micro-cel a
calcium silicate, synthetic
micro-cel t26
stabinex nw 7ps
micro-cel
toyofine a
micro-cel t41
micro-cel t38
starlex l
calsil
promaxon p60
micro-cel c
silmos t
calcium hydrosilicate
micro-cel t
dicalcium silicate
grammite
AKOS015915657
JHLNERQLKQQLRZ-UHFFFAOYSA-N
DTXSID5049570
DTXSID4029648 ,
Q416365
39433-03-9
dicalcium;silicate
dicalcium orthosilicate
synthetisch calciumsilicaat /dutch/
calcium pectolith
micro-cel t-41
head cold
mfcd00015979

Excerpt	Reference	Relevance
"Dicalcium silicate (Ca₂ SiO₄) has been reported as an interesting candidate for biomaterials use due to its attractive bioactive properties. "	( A synthesis route to nanoparticle dicalcium silicate for biomaterials research. Booncharoen, W; Jaroenworaluck, A; Stevens, R, 2011)	1.37

Occurs in Manufacturing (100 Items)

Item	Process	Frequency
Beverages	core-ingredient	373
Dried products to be rehydrated	core-ingredient	366
Dried products	core-ingredient	366
Dehydrated beverages	core-ingredient	364
Condiments	core-ingredient	96
Groceries	core-ingredient	89
Sugars	core-ingredient	49
Sweeteners	core-ingredient	49
Snacks	core-ingredient	23
Tea-based beverages	core-ingredient	21
Iced teas	core-ingredient	21
Salts	core-ingredient	13
Plant-based foods and beverages	core-ingredient	12
Plant-based foods	core-ingredient	9
Meals	core-ingredient	8
Dietary supplements	core-ingredient	8
Salty snacks	core-ingredient	8
Appetizers	core-ingredient	8
Iodised salts	core-ingredient	8
Crisps	core-ingredient	7
Chips and fries	core-ingredient	7
Lemon flavored iced teas	core-ingredient	7
Sodas	core-ingredient	6
Sauces	core-ingredient	6
Carbonated drinks	core-ingredient	5
Cereals and potatoes	core-ingredient	5
Bodybuilding supplements	core-ingredient	5
Table salts	core-ingredient	4
Lemonade	core-ingredient	4
Dips	core-ingredient	4
Teas	core-ingredient	3
Plant-based beverages	core-ingredient	3
Hot beverages	core-ingredient	3
Spice Mix	core-ingredient	3
Spices	core-ingredient	3
Artificially sweetened beverages	core-ingredient	3
Noodles	core-ingredient	3
Desserts	core-ingredient	3
Sweetened beverages	core-ingredient	3
Soups	core-ingredient	3
Pastas	core-ingredient	3
Cereals and their products	core-ingredient	3
Granulated sugars	core-ingredient	2
Sea salts	core-ingredient	2
Mixtures of herbs and spices	core-ingredient	2
Sugar substitutes	core-ingredient	2
Vitamins	core-ingredient	2
Food additives	core-ingredient	2
Rice dishes	core-ingredient	2
Corn chips	core-ingredient	2
Plant-based spreads	core-ingredient	1
Spreads	core-ingredient	1
Breakfasts	core-ingredient	1
Instant mashed potatoes	core-ingredient	1
Mashed potatoes	core-ingredient	1
Artificial sugar substitutes	core-ingredient	1
Purées	core-ingredient	1
Potato preparations	core-ingredient	1
Salted snacks	core-ingredient	1
Meats	core-ingredient	1
Meats and their products	core-ingredient	1
Powdered drink	core-ingredient	1
Dietary drink for sport	core-ingredient	1
Diet beverages	core-ingredient	1
Meat analogues	core-ingredient	1
Meat alternatives	core-ingredient	1
Macaroni and cheese	core-ingredient	1
Pasta dishes	core-ingredient	1
Gravy	core-ingredient	1
Dehydrated sauces	core-ingredient	1
Potato crisps	core-ingredient	1
Open Products Facts	core-ingredient	1
Non food products	core-ingredient	1
Instant noodles	core-ingredient	1
Vitamin Supplements	core-ingredient	1
Boissons lyophilisées	core-ingredient	1
Produits lyophilisés à reconstituer	core-ingredient	1
Produits déshydratés	core-ingredient	1
gazeuses	core-ingredient	1
Chicken seasoning	core-ingredient	1
Boissons	core-ingredient	1
drink mix powder	core-ingredient	1
Decaffeinated teas	core-ingredient	1
Creatine	core-ingredient	1
Fruit and vegetable preserves	core-ingredient	1
Confectioneries	core-ingredient	1
Sweet snacks	core-ingredient	1
en:energy-drinks	core-ingredient	1
Electrolytes	core-ingredient	1
Sweet spreads	core-ingredient	1
en:breads	core-ingredient	1
Crackers	core-ingredient	1
Frozen ready-made meals	core-ingredient	1
Meat lasagnas	core-ingredient	1
Pizzas	core-ingredient	1
Pizzas pies and quiches	core-ingredient	1
Protein powders	core-ingredient	1
Chips	core-ingredient	1
Japanese-style-peanuts	core-ingredient	1
Waters	core-ingredient	1

Role	Description
food anticaking agent	An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
antacid	Any substance which is used to neutralise stomach acidity.
flame retardant	Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
inorganic calcium salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (27.50)	29.6817
2010's	25 (62.50)	24.3611
2020's	4 (10.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (2.44%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	40 (97.56%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
hydrochloric acid Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.. hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.	2.08	1	chlorine molecular entity; gas molecular entity; hydrogen halide; mononuclear parent hydride	mouse metabolite
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	7.1	1	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
nickel Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.	2.05	1	metal allergen; nickel group element atom	epitope; micronutrient
nitrites Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)	2.08	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species	human metabolite
potassium chloride Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.. potassium chloride : A metal chloride salt with a K(+) counterion.	2.08	1	inorganic chloride; inorganic potassium salt; potassium salt	fertilizer
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2h-tetrazolium hydroxide 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide: structure given in first source	2.08	1
edetic acid Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.	2.1	1	ethylenediamine derivative; polyamino carboxylic acid; tetracarboxylic acid	anticoagulant; antidote; chelator; copper chelator; geroprotector
methylamine methyl group : An alkyl group that is the univalent group derived from methane by removal of a hydrogen atom.	2.08	1	methylamines; one-carbon compound; primary aliphatic amine	mouse metabolite
thiazoles [no description available]	2.08	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
limestone Calcium Carbonate: Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.. calcium carbonate : A calcium salt with formula CCaO3.	2.17	1	calcium salt; carbonate salt; inorganic calcium salt; one-carbon compound	antacid; fertilizer; food colouring; food firming agent
durapatite Durapatite: The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.. hydroxylapatite : A phosphate mineral with the formula Ca5(PO4)3(OH).	2.79	3
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	7.6	1	copper group element atom; elemental silver	Escherichia coli metabolite
chromium Chromium: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.. chromium ion : An chromium atom having a net electric charge.. chromium atom : A chromium group element atom that has atomic number 24.	2.8	3	chromium group element atom; metal allergen	micronutrient
sodium sulfate [no description available]	2.08	1	inorganic sodium salt
calcium phosphate, dibasic, anhydrous calcium phosphate, dibasic, anhydrous: molecular formula CaHPO(4), DCPA=dicalcium phosphate anhydrous; don't confuse with dichloropropionanilide which also is called DCPA; MW=136.06; has greater surface area and lower pH than DCPD (dicalcium phosphate dihydrate); occurs in nature as monetite; an intermediate in preparing hydroxyapatite	2.11	1	calcium phosphate
tricalcium phosphate tricalcium phosphate: a form of tricalcium phosphate used as bioceramic bone replacement material; see also records for alpha-tricalcium phosphate, beta-tricalcium phosphate, calcium phosphate; apatitic tricalcium phosphate Ca9(HPO4)(PO4)5(OH) is the calcium orthophosphate leading to beta tricalcium phosphate Ca3(PO4)2 (b-TCP). calcium phosphate : A calcium salt composed of calcium and phosphate/diphosphate ions; present in milk and used for the mineralisation of calcified tissues.	3.68	9	calcium phosphate
calcium sulfate Calcium Sulfate: A calcium salt that is used for a variety of purposes including: building materials, as a desiccant, in dentistry as an impression material, cast, or die, and in medicine for immobilizing casts and as a tablet excipient. It exists in various forms and states of hydration. Plaster of Paris is a mixture of powdered and heat-treated gypsum.	2.1	1	calcium salt; inorganic calcium salt
tricalcium silicate tricalcium silicate: might be used as injectable bioactive cement	9.8	9
vanadates Vanadates: Oxyvanadium ions in various states of oxidation. They act primarily as ion transport inhibitors due to their inhibition of Na(+)-, K(+)-, and Ca(+)-ATPase transport systems. They also have insulin-like action, positive inotropic action on cardiac ventricular muscle, and other metabolic effects.. vanadate(3-) : A vanadium oxoanion that is a trianion with formula VO4 in which the vanadium is in the +5 oxidation state and is attached to four oxygen atoms.	2.6	1	trivalent inorganic anion; vanadium oxoanion	EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
potassium phosphate potassium phosphate: used in dental materials and to treat hypophosphatemia; RN given refers to cpd with unspecified MF. tripotassium phosphate : An inorganic potassium salt that is the tripotassium salt of phosphoric acid.	2.08	1	inorganic phosphate salt; inorganic potassium salt
thiazolyl blue thiazolyl blue: RN & II refers to bromide. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide : The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.	2.08	1	organic bromide salt	colorimetric reagent; dye
zoledronic acid Zoledronic Acid: An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.. zoledronic acid : An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.	2.1	1	1,1-bis(phosphonic acid); imidazoles	bone density conservation agent
calcium aluminate [no description available]	2.76	3
calcium aluminate ferrite [no description available]	2.46	2
sodium bicarbonate Sodium Bicarbonate: A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.	2.08	1	one-carbon compound; organic sodium salt	antacid; food anticaking agent
alizarin red s Alizarin Red S: RN given refers to parent cpd; structure. alizarin red S : An organic sodium salt having 3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate as the counterion. It is commonly used to stain embryo skeletons in cleared whole mounts, usually of small mammals.	2.06	1	organic sodium salt; organosulfonate salt	histological dye
osteoprotegerin Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.	2.05	1	long-chain fatty acid
dinoprostone prostaglandin E2 : Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.	2.08	1	prostaglandins E	human metabolite; mouse metabolite; oxytocic
aluminum Aluminum: A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	2.03	1	boron group element atom; elemental aluminium; metal atom
bismuth Bismuth: A metallic element that has the atomic symbol Bi, and atomic number 83. Its principal isotope is Bismuth 209.	2.03	1	metal atom; pnictogen
sulfur Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.	2.08	1	chalcogen; nonmetal atom	macronutrient
silicon Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].	2.07	1	carbon group element atom; metalloid atom; nonmetal atom
chlorhexidine Chlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.. chlorhexidine : A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge.	2.1	1	biguanides; monochlorobenzenes	antibacterial agent; antiinfective agent
zeolites [no description available]	2.05	1
aluminum oxide Aluminum Oxide: An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.	2.03	1
silicate cement Silicate Cement: A relatively hard, translucent, restorative material used primarily in anterior teeth. (From Boucher's Clinical Dental Terminology, 4th ed, p50)	3	4
belite belite: a fly ash cement	7.05	1	inorganic calcium salt	antacid; flame retardant; food anticaking agent
ettringite ettringite: synthesis of ettringite from acid wastewaters of the aluminium anodising industry is a possible route of reducing the emissions to the environment, recovering at the same time resource materials as a useful marketable mineral	2.03	1

Condition	Relationship Strength	Studies
Demineralization, Tooth [description not available]	2.1	1
Autolysis, Dental Pulp [description not available]	2.1	1
Inflammation, Endodontic [description not available]	2.1	1
Dentin, Secondary Dentin formed by normal pulp after completion of root end formation.	2.1	1
Exposure, Dental Pulp [description not available]	2.1	1
Dental Pulp Exposure The result of pathological changes in the hard tissue of a tooth caused by carious lesions, mechanical factors, or trauma, which render the pulp susceptible to bacterial invasion from the external environment.	2.1	1
Pulpitis Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis.	2.1	1
Innate Inflammatory Response [description not available]	2.52	2
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	2.52	2

calcium silicate

Cross-References

Synonyms (53)

Research Excerpts

Effects

Occurs in Manufacturing (100 Items)

Roles (3)

Drug Classes (1)

Research

Studies (40)

Market Indicators

Research Demand Index: 73.18

Study Types

calcium silicate

Cross-References

Synonyms (53)

Research Excerpts

Effects

Occurs in Manufacturing (100 Items)

Roles (3)

Drug Classes (1)

Research

Studies (40)

Market Indicators

Research Demand Index: 73.18

Study Types

Related Drugs (38)

Related Conditions (9)