| Assay ID | Title | Year | Journal | Article |
|---|
| AID1892533 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in human THP-1 cells assessed as reduction in intracellular survival at 1 to 10 uM measured after 24 to 48 hrs | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14
| Cosolvent Sites-Based Discovery of |
| AID327883 | Effect on Phorbol 12-myristate 13-acetate-induced cellular morphology in mouse J774 macrophage cells at 20 uM by video microscopy | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327893 | Inhibition of human PDK1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327907 | Inhibition of human TGFbeta R1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327896 | Inhibition of human PKC zeta | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327906 | Inhibition of human AMPKalpha1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327909 | Inhibition of human EphA1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327904 | Inhibition of human MAPKAPK5 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327887 | Inhibition of Mycobacterium tuberculosis PKnG-I87S/A92S mutant at 25 uM by autoradiography | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327902 | Inhibition of human PAK4 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327890 | Inhibition of human JNK1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327900 | Inhibition of human MAP2K6 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327899 | Inhibition of human MAP2K1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327888 | Inhibition of human CDK2 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327894 | Inhibition of human PKCalpha | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID1892535 | Inhibition of full length Mycobacterium tuberculosis protein kinase G using His-tagged GarA as substrate in presence of [gamma32P] ATP measured after 12 to 24 hrs by radiometric kinase assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14
| Cosolvent Sites-Based Discovery of |
| AID327897 | Inhibition of human ROCK2 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327879 | Inhibition of Mycobacterium tuberculosis Protein kinase G by radiometric ATP consumptive assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327889 | Inhibition of human GSK3 beta | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID265353 | Inhibition of FLT3 | 2006 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 16, Issue:12
| Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. |
| AID327898 | Inhibition of human AKT1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327895 | Inhibition of human PKC mu | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327881 | Effect on protein translation in mouse J774 macrophage cells after 9 hrs | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327911 | Inhibition of human FGFR1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327903 | Inhibition of human MST4 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327886 | Inhibition of Mycobacterium tuberculosis PKnGdeltaN mutant at 63 uM by autoradiography | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327908 | Inhibition of human EGFR | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327910 | Inhibition of human FAK | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID265355 | Antiproliferative activity against human MV4-11 cells | 2006 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 16, Issue:12
| Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. |
| AID327892 | Inhibition of human CDK5 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327905 | Inhibition of human CHK1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327885 | Effect on Phorbol 12-myristate 13-acetate-induced macropinocytosis in mouse J774 macrophage cells at 20 uM by video microscopy | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327912 | Inhibition of human FLT3 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327901 | Inhibition of human PAK1 | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327882 | Effect on phagocytosis of latex beads in mouse J774 macrophage cells after 30 mins | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327891 | Inhibition of human p38alpha | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327884 | Effect on Phorbol 12-myristate 13-acetate-induced membrane ruffling in mouse J774 macrophage cells at 20 uM by video microscopy | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID327880 | Effect on proliferation in mouse J774 macrophage cells assessed as incorporation of [3H]thymidine after 48 hrs | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-17, Volume: 104, Issue:29
| Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |