Compounds > apupg
Page last updated: 2024-10-15

apupg

Cross-References

ID SourceID
PubMed CID135596625
MeSH IDM0067446

Synonyms (7)

Synonym
3494-35-7
apupg
einecs 222-488-6
adenylyl uridylyl guanosine
adenylyl-(3'.5')-uridylyl-(3'.5')-guanosine
adenylyl-(3'-->5')-uridylyl-(3'-->5')-guanosine
DTXSID501262490

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ExcerptReference
"ApUpG appears to inhibit by competing with endogenous globin mRNA for 80 S ribosomal couples, since the inhibition of protein synthesis by ApUpG can be largely relieved by increasing the globin mRNA."( Mechanism of inhibition of eukaryotic translational initiation by the trinucleotide ApUpG.
Gross, M; Sigler, PB; Wagner, T, 1989)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
puromycin
[no description available]		1.9710puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
adenylyl-(3'-5')-adenylyl-(3'-5')-adenosine
[no description available]		2.3720
oligonucleotides
[no description available]		2.3620
guanylyl imidodiphosphate
Guanylyl Imidodiphosphate: A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.. guanosine 5'-[beta,gamma-imido]triphosphate : A nucleoside triphosphate analogue that is GTP in which the oxygen atom bridging the beta- to the gamma- phosphate is replaced by a nitrogen atom A non-hydrolyzable analog of GTP, it binds tightly to G-protein in the presence of Mg(2+).		1.9510nucleoside triphosphate analogue
ConditionIndicatedRelationship StrengthStudiesTrials