6''-O-malonyldaidzin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
malonyldaidzin : A glycosyloxyisoflavone that is daidzein substituted by a 6-O-(carboxyacetyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 9913968 |
| CHEMBL ID | 3426719 |
| CHEBI ID | 80371 |
| MeSH ID | M0431145 |
| Synonym |
|---|
| malonyldaidzin |
| 6''-o-malonyldaidzin |
| 124590-31-4 |
| daidzin 6''-o-malonate |
| CHEBI:80371 , |
| 3-(4-hydroxyphenyl)-4-oxo-4h-1-benzopyran-7-yl 6-o-(carboxyacetyl)-beta-d-glucopyranoside |
| unii-54ce6owe7a |
| 3-(4-hydroxyphenyl)-4-oxo-4h-chromen-8-yl 6-o-(carboxyacetyl)-beta-d-glucopyranoside |
| 4h-1-benzopyran-4-one, 7-[[6-o-(2-carboxyacetyl)-.beta.-d-glucopyranosyl]oxy]-3-(4-hydroxyphenyl)- |
| 3-(4-hydroxyphenyl)-4-oxo-4h-chromen-8-yl 6-o-(carboxyacetyl)-.beta.-d-glucopyranoside |
| malonyldaidzin, (-)- |
| malonyl daidzin (constituent of soy isoflavones) [dsc] |
| 54CE6OWE7A , |
| CHEMBL3426719 |
| malonyl-daidzin |
| Q27149376 |
| malonyl daidzin |
| 6-o-malonyldaidzin |
| 3-oxo-3-(((2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-((3-(4-hydroxyphenyl)-4-oxo-4h-chromen-7-yl)oxy)tetrahydro-2h-pyran-2-yl)methoxy)propanoic acid |
| MS-29327 |
| HY-N4073 |
| CS-0030648 |
| 3-oxo-3-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-[3-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid |
| E88875 |
| DTXSID201319060 |
| AKOS040760360 |
| PD165367 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "The crude methanol extract of Pueraria lobata was investigated by dual high-resolution α-glucosidase inhibition and radical scavenging profiling combined with hyphenated HPLC-HRMS-SPE-NMR." | ( Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata. Jäger, AK; Kongstad, KT; Liu, B; Nyberg, NT; Qinglei, S; Staerk, D, 2015) | 0.42 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Despite considerable interest in the physiologic effects of isoflavones, the in vivo bioavailability of the most common isoflavone forms, malonylglucoside conjugates, has not been determined." | ( Malonylglucoside conjugates of isoflavones are much less bioavailable compared with unconjugated β-glucosidic forms in rats. Gallaher, DD; Ismail, B; Yerramsetty, V, 2014) | 0.4 |
| Role | Description |
|---|---|
| plant metabolite | Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| hydroxyisoflavone | Member of the class of isoflavones bearing at least one hydroxy group. |
| glycosyloxyisoflavone | A member of the class of isoflavones having one or more glycosyl residues attached at unspecified positions. |
| malonate ester | An ester of malonic acid; any compound containing a malonate ester skeleton. |
| monosaccharide derivative | A carbohydrate derivative that is formally obtained from a monosaccharide. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1204996 | Inhibition of Saccharomyces cerevisiae alpha-glucosidase type 1 assessed as 4-nitrophenol cleavage product by high-resolution biochromatogram | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata. |
| AID1204997 | Antioxidant activity of the compound assessed as inhibition of ABTS radicals after 20 mins by spectrophotometric analysis | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.06) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||