modified amino acid binding

Definition

Target type: molecularfunction

Binding to a modified amino acid. [GOC:mah]

Modified amino acid binding refers to the interaction of a protein or other molecule with an amino acid that has been chemically altered. These modifications can include phosphorylation, acetylation, methylation, glycosylation, and ubiquitination, among others. These modifications can change the chemical properties of the amino acid, affecting its ability to interact with other molecules.

Modified amino acids can play a variety of roles in cellular processes. For example, phosphorylation can activate or deactivate enzymes, while acetylation can regulate gene expression. Modified amino acids can also be involved in protein-protein interactions, signal transduction pathways, and other important biological processes.

Proteins that bind modified amino acids often have specific binding sites that recognize the modified amino acid. These sites can be composed of amino acid residues that interact with the modified group, as well as other residues that contribute to the overall shape and charge of the binding site.

The study of modified amino acid binding is important for understanding a wide range of biological processes. For example, understanding the mechanisms of protein phosphorylation is crucial for developing drugs that target specific kinases, which are enzymes that catalyze phosphorylation. Similarly, understanding the role of acetylation in gene regulation could lead to new therapies for cancer and other diseases.'
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Proteins (2)

Compounds (16)