Compounds > 6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazole
Page last updated: 2024-08-02 04:36:21

6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazole

Description

6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazole : no description available [CHeBI]

Cross-References

ID SourceID
PubMed CID6622296
CHEMBL ID1442084
CHEBI ID107063

Synonyms (26)

Synonym
CHEMDIV3_009833
IDI1_027743
smr000323243
MLS000684725 ,
CHEBI:107063
BRD-K94418733-001-01-8
F0647-0174
863001-18-7
HMS1500O21
AB00614502-02
6-bromo-2-pyrrolidin-1-yl-1,3-benzothiazole
HMS2710F06
AKOS015957079
bdbm93813
6-bromo-2-pyrrolidino-1,3-benzothiazole
cid_6622296
6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazole
6-bromanyl-2-pyrrolidin-1-yl-1,3-benzothiazole
6-bromo-2-(pyrrolidin-1-yl)-1,3-benzothiazole
CHEMBL1442084
Q27184978
sr-01000096765
SR-01000096765-1
6-bromo-2-(pyrrolidin-1-yl)benzo[d]thiazole
CS-0271778
EN300-237928

Drug Classes (1)

ClassDescription
benzothiazoles

Protein Targets (18)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Chain A, Beta-lactamaseEscherichia coli K-12Potency39.8107AID485341
LuciferasePhotinus pyralis (common eastern firefly)Potency7.5686AID588342
BRCA1Homo sapiens (human)Potency1.2589AID624202
ATAD5 protein, partialHomo sapiens (human)Potency2.0588AID504466; AID504467
TDP1 proteinHomo sapiens (human)Potency29.0929AID686978
Microtubule-associated protein tauHomo sapiens (human)Potency11.2202AID1460
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.8107AID1030
P53Homo sapiens (human)Potency70.7946AID504706
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency1.9953AID485313
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency4.6109AID504444
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency12.5893AID743266
huntingtin isoform 2Homo sapiens (human)Potency0.5623AID1688
ras-related protein Rab-9AHomo sapiens (human)Potency1.4125AID485297
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency89.1251AID588590
gemininHomo sapiens (human)Potency20.5962AID624296
TAR DNA-binding protein 43Homo sapiens (human)Potency15.8489AID652104

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Heat shock protein hsp-16.2Caenorhabditis elegansIC5064.0000AID651579
Protein skinhead-1Caenorhabditis elegansIC5052.6250AID624474; AID651563

Bioassays (10)

Assay IDTitleYearJournalArticle
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
ISSN: 1464-3405		Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
ISSN: 1872-9096		High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
ISSN: 1552-454X		A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
ethoxzolamide
0
aromatic ether;
benzothiazoles;
sulfonamide		antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor		00low000000
riluzole
0
benzothiazoles00low000000
tiaramide
0
benzothiazoles00low000000
ticlatone
0
benzothiazoles00low000000
benzothiazole
0
benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic		00low000000
dibenzothiazyl disulfide
0
benzothiazoles;
organic disulfide		allergen00low000000
2-aminobenzothiazole
0
benzothiazoles00low000000
diamthazole
0
benzothiazoles00low000000
dithiazanine
0
benzothiazoles;
benzothiazolium ion		anthelminthic drug;
fluorochrome		00low000000
2-(methylthio)benzothiazole
0
benzothiazoles;
methyl sulfide		aryl hydrocarbon receptor agonist;
xenobiotic metabolite		00low000000
2-(2-hydroxyphenyl)benzothiazole
0
benzothiazoles;
phenols		geroprotector00low000000
methabenzthiazuron
0
benzothiazoles00low000000
sabeluzole
0
benzothiazoles00low000000
lubeluzole
0
benzothiazoles00low000000
2-benzothiazolesulfonamide
0
benzothiazoles;
sulfonamide		00low000000
tioxidazole
0
benzothiazoles00low000000
2-(4-Morpholinyl)benzothiazole
0
benzothiazoles00low000000
mefenacet
0
benzothiazoles;
tertiary carboxamide		antimitotic;
herbicide		00low000000
firefly luciferin
0
1,3-thiazolemonocarboxylic acid;
benzothiazoles;
imidothioate		luciferin00low000000
pramipexole
0
benzothiazoles;
diamine		antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
radical scavenger		00low000000
N-(4-methoxyphenyl)-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
2-pyridin-4-yl-1,3-benzothiazole
0
benzothiazoles00low000000
6-methoxy-3-methyl-1,3-benzothiazol-2-imine
0
benzothiazoles00low000000
6-Fluoro-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
N-[2-(1-azepanyl)-1,3-benzothiazol-6-yl]carbamic acid ethyl ester
0
benzothiazoles00low000000
e 3040
0
benzothiazoles;
organic hydroxy compound;
pyridines;
secondary amino compound		anti-inflammatory drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
uricosuric drug		00low000000
E3040 glucuronide
0
benzothiazoles;
beta-D-glucosiduronic acid;
pyridines;
secondary amino compound		xenobiotic metabolite00low000000
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide
0
benzothiazoles00low000000
6-ethoxy-2-[(4-fluorophenyl)methylthio]-1,3-benzothiazole
0
benzothiazoles00low000000
6-propan-2-yl-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
3-(2-phenoxyethyl)-1,3-benzothiazol-2-one
0
benzothiazoles00low000000
3-[3-(2-methoxyphenoxy)propyl]-1,3-benzothiazol-2-one
0
benzothiazoles00low000000
2-(2-oxo-1,3-benzothiazol-3-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide
0
benzothiazoles00low000000
N-(1,3-benzothiazol-2-yl)-N-methylbenzamide
0
benzothiazoles00low000000
2-[(1-cyclohexyl-5-tetrazolyl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
0
benzothiazoles00low000000
2-(1,3-benzothiazol-2-yl)-3-methyl-2-butenenitrile
0
benzothiazoles00low000000
5-[(4-chloro-1-pyrazolyl)methyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-2-furancarboxamide
0
benzothiazoles00low000000
N-(2-furanylmethyl)-2-(2-oxo-1,3-benzothiazol-3-yl)acetamide
0
benzothiazoles00low000000
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-methoxyacetamide
0
benzothiazoles00low000000
N-(5-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamide
0
benzothiazoles00low000000
2-(4,5-dihydrothiazol-2-ylthio)-N-(6-methoxy-1,3-benzothiazol-2-yl)acetamide
0
benzothiazoles00low000000
2-(beta-D-glucosyl)benzothiazole
0
benzothiazoles;
C-glycosyl compound		00low000000
1-[(1,3-benzothiazol-2-ylthio)methyl]-2-azepanone
0
benzothiazoles00low000000
2-[[3-[4-(dimethylamino)phenyl]-4,5-dihydroisoxazol-5-yl]methyl]-1,1-dioxo-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
5-[(1,3-benzothiazol-2-ylthio)methyl]-2-furancarboxylic acid methyl ester
0
benzothiazoles00low000000
N-(4,6-dimethyl-2-pyrimidinyl)-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
captax
0
aryl thiol;
benzothiazoles		carcinogenic agent;
metabolite		00low000000
1,3-benzothiazol-2-yl(thiomorpholin-4-yl)methanone
0
benzothiazoles00low000000
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide
0
benzothiazoles00low000000
2-(1,3-benzothiazol-2-ylmethoxy)phenol
0
benzothiazoles00low000000
N-[2-(1-cyclohexenyl)ethyl]-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
0
benzothiazoles00low000000
N-(4-methyl-2-thiazolyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide
0
benzothiazoles00low000000
N-(1,3-benzothiazol-2-yl)-2-cyclohexylacetamide
0
benzothiazoles00low000000
N-(3-phenyl-1,3-benzothiazol-2-ylidene)-2-propenamide
0
benzothiazoles00low000000
N-(4-methoxyphenyl)-3-methyl-1,3-benzothiazol-2-imine
0
benzothiazoles00low000000
N-(6-ethoxy-1,3-benzothiazol-2-yl)butanamide
0
benzothiazoles00low000000
N-[[(6-methoxy-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-furancarboxamide
0
benzothiazoles00low000000
2-[(2-chlorophenyl)methylthio]-6-nitro-1,3-benzothiazole
0
benzothiazoles00low000000
N-(1,3-benzothiazol-2-yl)-2-[(1-methyl-2-imidazolyl)thio]acetamide
0
benzothiazoles00low000000
N-[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]-2-(methylthio)-1,3-benzothiazol-6-amine
0
benzothiazoles00low000000
2-[[cyclohexyl(oxo)methyl]amino]-1,3-benzothiazole-6-carboxylic acid methyl ester
0
benzothiazoles00low000000
N-(2-methyl-1,3-benzothiazol-6-yl)-2-furancarboxamide
0
benzothiazoles00low000000
2-(2,4,5-trimethoxyphenyl)-1,3-benzothiazole
0
benzothiazoles00low000000
3-[2-(3-methylphenoxy)ethyl]-1,3-benzothiazol-2-one
0
benzothiazoles00low000000
3-[2-(4-methylphenoxy)ethyl]-1,3-benzothiazol-2-one
0
benzothiazoles00low000000
3-methoxy-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)benzamide
0
benzothiazoles00low000000
N-(6-ethoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamide
0
benzothiazoles00low000000
N-[6-(diethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide
0
benzothiazoles00low000000
2-[(3-bromo-2-imidazo[1,2-a]pyrimidinyl)methylthio]-1,3-benzothiazole
0
benzothiazoles00low000000
N-(6-chloro-1,3-benzothiazol-2-yl)-2-diphenylphosphorylacetamide
0
benzothiazoles00low000000
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thione
0
benzothiazoles00low000000
6-fluoro-2-phenyl-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
1-[[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]amino]-3-phenylthiourea
0
benzothiazoles00low000000
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl ester
0
benzothiazoles00low000000
[4-methoxy-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide
0
benzothiazoles00low000000
[4-chloro-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide
0
benzothiazoles00low000000
(4,7-dichloro-1,3-benzothiazol-2-yl)hydrazine
0
benzothiazoles00low000000
3,4,5-trimethoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamide
0
benzothiazoles00low000000
4-(1,3-benzothiazol-2-ylthio)butanoic acid [2-[(3-cyano-2-thiophenyl)amino]-2-oxoethyl] ester
0
benzothiazoles00low000000
N-[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]-1-methyl-2-pyrrolecarboxamide
0
benzothiazoles00low000000
3-(1,3-benzothiazol-2-yl)propanoic acid (3,5-dimethyl-4-isoxazolyl)methyl ester
0
benzothiazoles00low000000
1-(1,3-benzothiazol-2-yl)-3-propylurea
0
benzothiazoles00low000000
5-bromo-N-(6-sulfamoyl-1,3-benzothiazol-2-yl)-2-furancarboxamide
0
benzothiazoles00low000000
N-(4,7-dimethoxy-3-methyl-1,3-benzothiazol-2-ylidene)butanamide
0
benzothiazoles00low000000
N-(4-fluoro-3-methyl-1,3-benzothiazol-2-ylidene)-2-nitrobenzamide
0
benzothiazoles00low000000
5-bromo-N-(4,7-dimethoxy-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide
0
benzothiazoles00low000000
N-[2-(methylthio)-1,3-benzothiazol-6-yl]-2-furancarboxamide
0
benzothiazoles00low000000
1-cyclohexyl-3-(6-ethoxy-1,3-benzothiazol-2-yl)urea
0
benzothiazoles00low000000
5-bromo-N-(4-methoxy-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide
0
benzothiazoles00low000000
2-(1,3-benzothiazol-2-yl)-5-methyl-3-pyrazolamine
0
benzothiazoles00low000000
2-[5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl(oxo)methyl]-1,1-dioxo-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-4-oxo-4-thiophen-2-ylbutanamide
0
benzothiazoles00low000000
N-(2-phenylethyl)-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
N-(4,5,6-trifluoro-1,3-benzothiazol-2-yl)-2-furancarboxamide
0
benzothiazoles00low000000
4-[[5-(1,3-benzothiazol-2-yl)-2-thiophenyl]-oxomethyl]-1-piperazinecarboxaldehyde
0
benzothiazoles00low000000
1,3-benzothiazole-6-carboxylic acid (2-benzamido-2-oxoethyl) ester
0
benzothiazoles00low000000
1,3-benzothiazole-6-carboxylic acid [2-[(3,5-dichloro-4-methyl-2-pyridinyl)amino]-2-oxoethyl] ester
0
benzothiazoles00low000000
1,3-benzothiazole-6-carboxylic acid [2-(2-furanyl)-2-oxoethyl] ester
0
benzothiazoles00low000000
1-(1,1-dioxo-1,2-benzothiazol-3-yl)-N-(2-methylphenyl)-4-piperidinecarboxamide
0
benzothiazoles00low000000
N-(2-methyl-1,3-benzothiazol-6-yl)benzamide
0
benzothiazoles00low000000
2-(2-chloro-3-pyridinyl)-1,3-benzothiazole
0
benzothiazoles00low000000
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide
0
benzothiazoles00low000000
N-[6-(dimethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide
0
benzothiazoles00low000000
1,3-benzothiazole-6-carboxylic acid [2-[1-(1-methoxypropan-2-yl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester
0
benzothiazoles00low000000
N-(3-methyl-1,3-benzothiazol-2-ylidene)-2-pyrazinecarboxamide
0
benzothiazoles00low000000
2-(6-imidazo[2,1-b]thiazolyl)acetic acid [2-(1,3-benzothiazol-2-ylamino)-2-oxoethyl] ester
0
benzothiazoles00low000000
N-(1,3-benzothiazol-2-yl)-2-oxolanecarboxamide
0
benzothiazoles00low000000
1-(2-furanylmethyl)-N-[2-(methylthio)-1,3-benzothiazol-6-yl]-5-oxo-3-pyrrolidinecarboxamide
0
benzothiazoles00low000000
1-thiophen-2-ylsulfonyl-4-piperidinecarboxylic acid 1,3-benzothiazol-2-ylmethyl ester
0
benzothiazoles00low000000
N-(1,3-benzothiazol-2-yl)-2-methoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide
0
benzothiazoles00low000000
4-[[2-(4-methyl-1-piperidinyl)-1,3-benzothiazol-6-yl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester
0
benzothiazoles00low000000
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl ester
0
benzothiazoles00low000000
4-(4,6-difluoro-1,3-benzothiazol-2-yl)morpholine
0
benzothiazoles00low000000
5-bromo-2-thiophenecarboxylic acid 1,3-benzothiazol-2-ylmethyl ester
0
benzothiazoles00low000000
N-(6-acetamido-3-prop-2-enyl-1,3-benzothiazol-2-ylidene)cyclohexanecarboxamide
0
benzothiazoles00low000000
N-(6-acetamido-3-prop-2-enyl-1,3-benzothiazol-2-ylidene)-2-thiophenecarboxamide
0
benzothiazoles00low000000
2-chloro-N-(3-methyl-1,3-benzothiazol-2-ylidene)acetamide
0
benzothiazoles00low000000
2-(1,3-benzothiazol-2-ylmethylthio)-1-butyl-5-benzimidazolesulfonamide
0
benzothiazoles00low000000
N-(5-phenyl-1,3,4-oxadiazol-2-yl)-1,3-benzothiazole-2-carboxamide
0
benzothiazoles00low000000
3-methoxy-N-(3-methyl-6-methylsulfonyl-1,3-benzothiazol-2-ylidene)benzamide
0
benzothiazoles00low000000
[4-(butan-2-ylamino)-6-chloro-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide
0
benzothiazoles00low000000
N-[3-(2-methoxyethyl)-6-methylsulfonyl-1,3-benzothiazol-2-ylidene]-2-nitrobenzamide
0
benzothiazoles00low000000
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)benzohydrazide
0
benzothiazoles00low000000
3-chloro-N-[3-(2-methoxyethyl)-6-sulfamoyl-1,3-benzothiazol-2-ylidene]-1-benzothiophene-2-carboxamide
0
benzothiazoles00low000000
N-(7-methyl-2-thiazolo[4,5-g][1,3]benzothiazolyl)propanamide
0
benzothiazoles00low000000
N-[3-(2-methylcyclohexyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
N-(6-fluoro-1,3-benzothiazol-2-yl)-2-oxolanecarboxamide
0
benzothiazoles00low000000
N-(6-methyl-1,3-benzothiazol-2-yl)-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide
0
benzothiazoles00low000000
4-[[1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-piperidinyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester
0
benzothiazoles00low000000
2-[[4-methyl-5-[(2-oxo-1,3-benzothiazol-3-yl)methyl]-1,2,4-triazol-3-yl]thio]-N-(phenylmethyl)acetamide
0
benzothiazoles00low000000
N-(2-oxolanylmethyl)-2-(1-piperidinyl)-1,3-benzothiazole-6-carboxamide
0
benzothiazoles00low000000
N-(6-methyl-1,3-benzothiazol-2-yl)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[c]pyrazol-2-yl)acetamide
0
benzothiazoles00low000000
N-(4-methyl-1,3-benzothiazol-2-yl)-2-(1-pyrrolyl)acetamide
0
benzothiazoles00low000000
dithiazanine iodide
0
benzothiazoles;
organic iodide salt		anthelminthic drug;
fluorochrome		00low000000
3,3'-diethylthiacarbocyanine iodide
0
benzothiazoles;
cyanine dye		fluorochrome00low000000
tyrphostin ag825
0
aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide		epidermal growth factor receptor antagonist00low000000
2-(1,3-benzothiazol-2-yl)-4-chloro-5-(3-chloroanilino)-3-pyridazinone
0
benzothiazoles00low000000
5-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-3-methyl-2-thiophenecarboxylic acid ethyl ester
0
benzothiazoles00low000000
6-fluoro-N-phenyl-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
N'-(4-fluoro-1,3-benzothiazol-2-yl)-2-phenoxyacetohydrazide
0
benzothiazoles00low000000
N'-(4,5-dimethyl-1,3-benzothiazol-2-yl)propanehydrazide
0
benzothiazoles00low000000
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)propanehydrazide
0
benzothiazoles00low000000
4-fluoro-N-(4-fluoro-1,3-benzothiazol-2-yl)-1,3-benzothiazol-2-amine
0
benzothiazoles00low000000
N-[3-(dimethylamino)propyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide
0
benzothiazoles00low000000
2-(3,5-dimethyl-1H-pyrrol-2-yl)-1,3-benzothiazole
0
benzothiazoles00low000000
N-(6-methoxy-1,3-benzothiazol-2-yl)-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamide
0
benzothiazoles00low000000
r 115866
0
aromatic amine;
benzothiazoles;
secondary amino compound;
triazoles		00low000000
as 601245
0
benzothiazoles00low000000
2-(4-methoxyphenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
2-(4-chlorophenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
tozadenant
0
benzothiazoles00low000000
3-(benzenesulfonyl)-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]propanamide
0
benzothiazoles00low000000
2-(4-fluorophenyl)-6-methoxy-1,3-benzothiazole
0
benzothiazoles00low000000
2-(3-chlorophenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
vizamyl
0
(18)F radiopharmaceutical;
aromatic amine;
benzothiazoles;
secondary amino compound		radioactive imaging agent00low000000
picogreen
0
benzothiazoles;
cyanine dye;
quinolines;
tertiary amine		fluorescent dye00low000000
3,3'-diethylthiacarbocyanine iodide
0
benzothiazoles;
cyanine dye		fluorochrome00low000000
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-2-(1-piperidinyl)-1,3-benzothiazole-6-carboxamide
0
benzothiazoles00low000000
5-fluoro-2-phenyl-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
2-(2-fluorophenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
2-(4-fluorophenyl)-1,2-benzothiazol-3-one
0
benzothiazoles00low000000
INDY
0
benzothiazoles;
enone;
organic hydroxy compound		antineoplastic agent;
drug metabolite;
EC 2.7.12.1 (dual-specificity kinase) inhibitor		00low000000
2-(3-oxo-1,2-benzothiazol-2-yl)-N-phenylacetamide
0
benzothiazoles00low000000
tak-632
0
(trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor		00low000000
N-[3-(1,3-benzothiazol-2-yl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-2-yl]acetamide
0
benzothiazoles00low000000
ML355
0
benzothiazoles;
monomethoxybenzene;
phenols;
secondary amino compound;
substituted aniline;
sulfonamide		EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
platelet aggregation inhibitor		00low000000
dehydroluciferin
0
1,3-thiazolemonocarboxylic acid;
benzothiazoles;
biaryl;
phenols		animal metabolite;
luciferin		00low000000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Anemia, Fanconi0
1
201620168.0medium000010
Encephalitis, Polio0
1
2011201113.0medium000010
Fanconi Anemia0
1
201620168.0medium000010
Inflammation0
1
2010201014.0medium000100
Innate Inflammatory Response0
1
2010201014.0medium000100
Poliomyelitis0
1
2011201113.0medium000010