Page last updated: 2024-10-06

superpathway of sterol biosynthesis

Proteins (0)

Compounds (40)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
NADH
ergosterolA steroid occurring in FUNGI. Irradiation with ULTRAVIOLET RAYS results in formation of ERGOCALCIFEROL (vitamin D2).
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
squaleneA natural 30-carbon triterpene.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
presqualene pyrophosphate
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
alpha-Ketoglutarate
isovaleryl-coenzyme a
formic acidRN given refers to parent cpd
2-keto-4-methylvalerate
5-diphosphomevalonic acidRN given refers to ion(1-)
fecosterolRN given refers to (3beta,5alpha)-isomer
24-dehydroprovitamin D3
4,4-dimethylcholesta-8,14,24-trienola meiosis activating sterol; RN given refers to (5alpha,3beta)-isomer
3-hydroxy-3-methylglutaryl-coenzyme aRN given refers to cpd without isomeric designation
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
geranyl pyrophosphateRN given refers to (E)-isomer
Mevalonate
2,3-oxidosqualenean oxidized derivative of SQUALENE that can fold in several ways: chair-boat-chair-boat to LANOSTEROL; chair-chair-chair-boat to dammarane; or all chair to hopane and on to cycloartenol; RN given refers to (all-Z)-isomer
glutamate
leucineAn essential branched-chain amino acid important for hemoglobin formation.
acetoacetate
lanosterolA triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS.
Coenzyme A
s-adenosylhomocysteine5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
phosphomevalonate
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils
3,3-dimethylallyl pyrophosphateisomeric with isopentenyl pyrophosphate
acetoacetyl coa
zymosterola 4,14-desmethyl intermediate between LANOSTEROL and CHOLESTEROL