Page last updated: 2024-10-06

superpathway of L-tyrosine biosynthesis

Proteins (15)

ProteinSynonymsTaxonomy
3-dehydroquinate synthaseDHQS; EC 4.2.3.4Escherichia coli K-12
3-phosphoshikimate 1-carboxyvinyltransferaseEC 2.5.1.19; 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPSEscherichia coli K-12
3-dehydroquinate dehydratase3-dehydroquinase; EC 4.2.1.10; Type I DHQase; Type I dehydroquinase; DHQ1Escherichia coli K-12
Aspartate aminotransferaseAspAT; EC 2.6.1.1; Transaminase AEscherichia coli K-12
Chorismate synthaseCS; EC 4.2.3.5; 5-enolpyruvylshikimate-3-phosphate phospholyase; EPSP phospholyaseEscherichia coli K-12
Bifunctional chorismate mutase/prephenate dehydrataseChorismate mutase-prephenate dehydratase; P-proteinEscherichia coli K-12
Shikimate kinase 1SK 1; EC 2.7.1.71; Shikimate kinase I; SKIEscherichia coli K-12
Shikimate kinase 2SK 2; EC 2.7.1.71; Shikimate kinase II; SKIIEscherichia coli K-12
Aromatic-amino-acid aminotransferaseARAT; AROAT; EC 2.6.1.57; Beta-methylphenylalanine transaminase; 2.6.1.107Escherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitiveEC 2.5.1.54; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolaseEscherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitiveEC 2.5.1.54; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolaseEscherichia coli K-12
T-proteinEscherichia coli K-12
Quinate/shikimate dehydrogenaseEC 1.1.1.282; NAD-dependent shikimate 5-dehydrogenaseEscherichia coli K-12
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitiveEC 2.5.1.54; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolaseEscherichia coli K-12
Shikimate dehydrogenase (NADP(+))SD; SDH; EC 1.1.1.25Escherichia coli K-12

Compounds (32)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
Succinate
NADH
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
chlorineAn element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.
serum p-componentclose relation to C reactive protein; may be ovosomucoid
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
2,4,6-Trinitrobenzene Sulfonate
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Excitatory Postsynaptic PotentialsDepolarization of membrane potentials at the SYNAPTIC MEMBRANES of target neurons during neurotransmission. Excitatory postsynaptic potentials can singly or in summation reach the trigger threshold for ACTION POTENTIALS.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
diethyl pyrocarbonatePreservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.
sodium borohydrideRN given refers to parent cpd
alpha-keto-isovaleric acid
TolbutamideA sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
glutamate
prephenate
3-dehydroshikimate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
4-hydroxyphenylpyruvate
bromopyruvate
glyphosateactive cpd in herbicidal formulation Roundup; inhibits EC 2.5.1.19, 5-enolpyruvylshikimate-3-phosphate synthase; structure
flavin mononucleotide hydroquinonestructure in first source