Page last updated: 2024-10-06

coumarins biosynthesis (engineered)

Proteins (8)

ProteinSynonymsTaxonomy
Probable caffeoyl-CoA O-methyltransferase At4g26220EC 2.1.1.104; Trans-caffeoyl-CoA 3-O-methyltransferase; CCoAMT; CCoAOMTArabidopsis thaliana (thale cress)
4-hydroxyphenylacetate 3-monooxygenase oxygenase componentEC 1.14.14.9; 4-HPA 3-hydroxylase; 4-HPA 3-monooxygenase large componentEscherichia coli
Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase F6H2-1-1IbF6H2-1-1; EC 1.14.11.61; EC 1.14.11.62; 2-oxoglutarate-dependent dioxygenase F6H2-1-1; 2OGD F6H2-1-1Ipomoea batatas (sweet potato)
Feruloyl CoA ortho-hydroxylase 1EC 1.14.11.61Arabidopsis thaliana (thale cress)
4-coumarate--CoA ligase 14CL 1; EC 6.2.1.12; 4-coumarate--CoA ligase isoform 1; At4CL1; 4-coumaroyl-CoA synthase 1Arabidopsis thaliana (thale cress)
4-coumarate--CoA ligase 24CL 2; EC 6.2.1.12; 4-coumarate--CoA ligase isoform 2; At4CL2; 4-coumaroyl-CoA synthase 2Arabidopsis thaliana (thale cress)
4-coumarate--CoA ligase 14CL 1; EC 6.2.1.12; 4-coumaroyl-CoA synthase 1Petroselinum crispum (parsley)
Phenylalanine ammonia lyase Rhodotorula glutinis

Compounds (22)

CompoundDescription
diphosphoric acid
hydronium ion
Succinate
Ammonium
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
1,5-dihydro-FADchromophore component of E coli DNA photolyase
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
alpha-Ketoglutarate
scopoletinPlant growth factor derived from the root of Scopolia carniolica or Scopolia japonica.
esculetinused in filters for absorption of ultraviolet light; structure
7-hydroxycoumarinactive metabolite of coumarin; RN given refers to parent cpd
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
feruloyl-coa
4-coumaroyl-coenzyme astructure given in first source
caffeoyl-coenzyme Astructure given in first source
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)