Page last updated: 2024-10-06

Sphingolipid pathway

Proteins (3)

ProteinSynonymsTaxonomy
Ceramide glucosyltransferaseEC 2.4.1.80; GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferaseHomo sapiens (human)
Phosphatidylcholine:ceramide cholinephosphotransferase 2EC 2.7.8.27; Sphingomyelin synthase 2Homo sapiens (human)
Phosphatidylcholine:ceramide cholinephosphotransferase 1 EC 2.7.8.27; Medulla oblongata-derived protein; Protein Mob; Sphingomyelin synthase 1; Transmembrane protein 23Homo sapiens (human)

Compounds (11)

CompoundDescription
phosphorylethanolamineRN given refers to parent cpd; structure
ketodihydrosphingosineRN given refers to cpd without isomeric designation
sphingosineAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
sphingosine 1-phosphateRN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89
n-palmitoylsphingosinestructure given in first source; RN given refers to (R*,S*-(E))-isomer
serineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
n-stearoylsphingomyelin
palmitoyl coenzyme aA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
dihydrosphingosine 1-phosphateRN given refers to (R-(R*,S*))-isomer
mephentermineA sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.
dihydroceramidelacks the 4-5 trans double bond of the sphingosine moiety of ceramides; structure in first source