Compounds > n-stearoylsphingomyelin
Page last updated: 2024-12-11

n-stearoylsphingomyelin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,3-(N-steroylsphingosyl)-1-phosphocholine: RN & structure given in first source; RN not in Chemline 12/87 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

N-stearoylsphingosine-1-phosphocholine : A sphingomyelin d18:1 in which the ceramide N-acyl group is specified as stearoyl (octadecanoyl). [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

sphingomyelin 18:0 : A sphingomyelin in which the total number of carbons in the sphingoid base and fatty acyl groups is 18 with 0 double bonds. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID6453725
CHEMBL ID1609656
CHEBI ID83358
SCHEMBL ID14889266
MeSH IDM0103076

Synonyms (49)

Synonym
LMSP03010001
n-(octadecanoyl)-sphing-4-enine-1-phosphocholine
c18 sphingomyelin
sm(d18:1/18:0)
NCGC00161363-01
2,3-sppc
n-stearoyl-d-erythro-sphingosylphosphorylcholine
58909-84-5
BML3-D05
[(e,2s,3r)-3-hydroxy-2-(octadecanoylamino)octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate
sphingomyelin 18:0
05ug6280ni ,
3,5-dioxa-8-aza-4-phosphahexacosan-1-aminium, 4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-n,n,n-trimethyl-9-oxo-, hydroxide, inner salt, 4-oxide, (r-(r*,s*-(e)))-
stearoylsphingomyelin
n-stearoylsphingosine-phosphorylcholine
2,3-(n-steroylsphingosyl)-1-phosphocholine
unii-05ug6280ni
3,5-dioxa-8-aza-4-phosphahexacosan-1-aminium, 4-hydroxy-7-((1r,2e)-1-hydroxy-2-hexadecenyl)-n,n,n-trimethyl-9-oxo-, inner salt, 4-oxide, (7s)-
n-stearoylsphingomyelin
sphingomyelins n-stearoylsphingomyelin [mi]
n-stearoylsphingosine-1-phosphocholine
3,5-dioxa-8-aza-4-phosphahexacosan-1-aminium, 4-hydroxy-7-(1-hydroxy-2-hexadecenyl)-n,n,n-trimethyl-9-oxo-, inner salt, 4-oxide, (r-(r*,s*-(e)))-
n-octadecanoylsphing-4-enine-1-phosphocholine
stearoyl sphingomyelin
(2s,3r,4e)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 2-(trimethylazaniumyl)ethyl phosphate
n-stearoylsphing-4-enine-1-phosphocholine
sphingomyelin (d18:1/18:0)
(2s,3r,4e)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 2-(trimethylammonio)ethyl phosphate
CHEBI:83358 ,
n-octadecanoylsphingosine-1-phosphocholine
SCHEMBL14889266
CHEMBL1609656
AS-60769
(2-{[(2s,3r,4e)-3-hydroxy-2-octadecanamidooctadec-4-en-1-yl phosphonato]oxy}ethyl)trimethylazanium
sm d36:1
18:0 sm (d18:1/18:0), n-stearoyl-d-erythro-sphingosylphosphorylcholine, powder
brain sm, sphingomyelin (brain, porcine), powder
ethanaminium, 2-[[hydroxy[[(2r,3s,4e)-3-hydroxy-2-[(1-oxooctadecyl)amino]-4-octadecen-1-yl]oxy]phosphinyl]oxy]-n,n,n-trimethyl-, inner salt, rel-
134731-80-9
Q27156784
sphingomyelin from bovine brain
n-octadecanoylsphingosylphosphorylcholine
n-acyl-4-sphingenyl-1-o-phosphorylcholine;n-acyl-d-sphingosine-1-phosphocholine
AKOS037645436
CS-0621186
HY-148388
DTXSID501313528
sphingomyelin (bovine spinal cord)
ethanaminium,2-[[hydroxy[[(2r,3s,4e)-3-hydroxy-2-[(1-oxooctadecyl)amino]-4-octadecen-1-yl]oxy]phosphinyl]oxy]-n,n,n-trimethyl-,innersalt,rel-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
mouse metaboliteAny mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
sphingomyelin 36:1A sphingomyelin in which the total number of carbons in the sphingoid base and fatty acyl groups is 36 with 1 double bond.
sphingomyelin d18:1Any sphingomyelin having sphingosine as the sphingoid component.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (4)

PathwayProteinsCompounds
Sphingolipid metabolism (integrated pathway)1167
Sphingolipid metabolism: integrated pathway163
Sphingolipid pathway315
Sphingolipids metabolism pathway063

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency44.66840.003245.467312,589.2998AID2517
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.96 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzyl alcohol
Benzyl Alcohol: A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.. hydroxytoluene : Any member of the class of toluenes carrying one or more hydroxy substituents.. benzyl alcohol : An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.. aromatic alcohol : Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.. aromatic primary alcohol : Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.		2.1310benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
choline
[no description available]		1.9710cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
erythrosine
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.		2.1310
stearic acid
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.		210long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
1,2-dipalmitoylphosphatidylcholine
1,2-Dipalmitoylphosphatidylcholine: Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.		2.3820
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		2.4420dihydrogen
fluorexon
fluorexon: structure		2.1310xanthene dyefluorochrome
1,2-distearoyllecithin
[no description available]		1.9810
sphingosine
sphing-4-enine : A sphingenine in which the C=C double bond is located at the 4-position.. sphingenine : A 2-aminooctadecene-1,3-diol having (2S,3R)-configuration.. sphingoid : Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds.. 2-aminooctadec-4-ene-1,3-diol : A 2-aminooctadecene-1,3-diol having its double bond at position 4.		1.9710sphing-4-eninehuman metabolite;
mouse metabolite
1,2-oleoylphosphatidylcholine
1,2-oleoylphosphatidylcholine: RN given refers to (Z,Z)-isomer. dioleoyl phosphatidylcholine : A phosphatidylcholine in which the phosphatidyl acyl groups are both oleoyl.		2.4620phosphatidylcholine(1+)
dimyristoylphosphatidylcholine
1,2-di-O-myristoyl-sn-glycero-3-phosphocholine : A 1,2-diacyl-sn-glycero-3-phosphocholine where the two phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).. dimyristoyl phosphatidylcholine : A phosphatidylcholine where the phosphatidyl acyl groups are specified as tetradecanoyl (myristoyl).		2.13101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
1-palmitoyl-2-linoleoylphosphatidylcholine
[no description available]		2.1310
samarium
sphingomyelin 16:0 : A sphingomyelin in which the total number of carbons contained in the sphingoid base and fatty acyl groups is 16 with zero double bonds.. sphingomyelin d18:1/16:0 : A sphingomyelin d18:1 in which the fatty acyl group contains 16 carbons and is fully saturated.. N-hexadecanoylsphingosine-1-phosphocholine : A sphingomyelin 34:1 in which the N-acyl group and sphingoid base are specified as hexadecanoyl and sphingosine respectively.		2.1310sphingomyelin d18:1/16:0mouse metabolite
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		3.26601,2-diacyl-sn-glycero-3-phosphocholine
phosphatidylcholines
1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine: RN given refers to (Z)-isomer. 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine : A phosphatidylcholine 36:1 in which the phosphatidyl acyl groups at positions 1 and 2 are stearoyl and oleoyl respectively.		1.98101-acyl-2-oleoyl-sn-glycero-3-phosphocholine betaine;
1-octadecanoyl-2-octadecenoyl-sn-glycero-3-phosphocholine
glycolipids
[no description available]		3.690
ConditionIndicatedRelationship StrengthStudiesTrials