Page last updated: 2024-10-06

Lysine catabolism

Proteins (10)

ProteinSynonymsTaxonomy
Glutaryl-CoA dehydrogenase, mitochondrialGCD; EC 1.3.8.6Homo sapiens (human)
Mitochondrial 2-oxodicarboxylate carrierSolute carrier family 25 member 21Homo sapiens (human)
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrialKAT/AadAT; 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; 2.6.1.39; Alpha-aminoadipate aminotransferase; AadAT; Kynurenine aminotransferase II; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; 2.6.1.7; Homo sapiens (human)
Peroxisomal sarcosine oxidasePSO; EC 1.5.3.1; EC 1.5.3.7; L-pipecolate oxidase; L-pipecolic acid oxidaseHomo sapiens (human)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrialEC 2.3.1.61; 2-oxoglutarate dehydrogenase complex component E2; OGDC-E2; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2KHomo sapiens (human)
Hydroxylysine kinase5-hydroxy-L-lysine kinase; EC 2.7.1.81; Aminoglycoside phosphotransferase domain-containing protein 1Homo sapiens (human)
Alpha-aminoadipic semialdehyde dehydrogenaseAlpha-AASA dehydrogenase; EC 1.2.1.31; Aldehyde dehydrogenase family 7 member A1; 1.2.1.3; Antiquitin-1; Betaine aldehyde dehydrogenase; 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; P6c dehydrogenaseHomo sapiens (human)
Ketimine reductase mu-crystallinEC 1.5.1.25; NADP-regulated thyroid-hormone-binding proteinHomo sapiens (human)
5-phosphohydroxy-L-lysine phospho-lyaseEC 4.2.3.134; Alanine--glyoxylate aminotransferase 2-like 2Homo sapiens (human)
Alpha-aminoadipic semialdehyde synthase, mitochondrialLKR/SDHHomo sapiens (human)

Compounds (22)

CompoundDescription
hydronium ion
NADH
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
1,5-dihydro-FADchromophore component of E coli DNA photolyase
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
2-amino-4-(2-aminoethoxy)butanoic acid, (DL)-isomer
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
saccharopinelysine precursor in the aminoadipic acid-lysine pathway in yeast; minor descriptor (75-85); on-line & Index Medicus search LYSINE/analogs & derivatives (75-85); RN given refers to (L)-isomer
alpha-Ketoglutarate
glutamate
alpha-ketoadipic acid
lipoamideRN given refers to cpd without isomeric designation
Coenzyme A
glutaryl-coenzyme A
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
creolinfrom refined coal tar oils