Page last updated: 2024-10-06

Heme signaling

Proteins (29)

ProteinSynonymsTaxonomy
Apolipoprotein B-100Apo B-100Homo sapiens (human)
Histone deacetylase 3HD3; EC 3.5.1.98; RPD3-2; SMAP45Homo sapiens (human)
Nuclear receptor ROR-alphaNuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alphaHomo sapiens (human)
NAD-dependent protein deacetylase sirtuin-1hSIRT1; EC 2.3.1.286; NAD-dependent protein deacylase sirtuin-1; 2.3.1.-; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XR1Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1Homo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6Homo sapiens (human)
Heme oxygenase 1HO-1; EC 1.14.14.18Homo sapiens (human)
Retinoic acid receptor RXR-alphaNuclear receptor subfamily 2 group B member 1; Retinoid X receptor alphaHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Exportin-1Exp1; Chromosome region maintenance 1 protein homologHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Apolipoprotein A-IApo-AI; ApoA-I; Apolipoprotein A1Homo sapiens (human)
Transcription factor MafK Erythroid transcription factor NF-E2 p18 subunitHomo sapiens (human)
Toll-like receptor 4EC 3.2.2.6; hTollHomo sapiens (human)
Nuclear receptor corepressor 1N-CoR; N-CoR1Homo sapiens (human)
Nuclear receptor subfamily 1 group D member 1Rev-erbA-alpha; V-erbA-related protein 1; EAR-1Homo sapiens (human)
Proton-coupled folate transporterG21; Heme carrier protein 1; PCFT/HCP1; Solute carrier family 46 member 1Homo sapiens (human)
Lymphocyte antigen 96Ly-96; ESOP-1; Protein MD-2Homo sapiens (human)
Transcription regulator protein BACH1BTB and CNC homolog 1; HA2303Homo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-2cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1Homo sapiens (human)
Hemoglobin subunit betaBeta-globin; Hemoglobin beta chainHomo sapiens (human)
Hemoglobin subunit alphaAlpha-globin; Hemoglobin alpha chainHomo sapiens (human)
Circadian locomoter output cycles protein kaputhCLOCK; EC 2.3.1.48; Class E basic helix-loop-helix protein 8; bHLHe8Homo sapiens (human)
Aryl hydrocarbon receptor nuclear translocator-like protein 1Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3Homo sapiens (human)
Neuronal PAS domain-containing protein 2Neuronal PAS2; Basic-helix-loop-helix-PAS protein MOP4; Class E basic helix-loop-helix protein 9; bHLHe9; Member of PAS protein 4; PAS domain-containing protein 4Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XSMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linkedHomo sapiens (human)
Nuclear receptor-interacting protein 1Nuclear factor RIP140; Receptor-interacting protein 140Homo sapiens (human)
Retinoic acid-induced protein 1Homo sapiens (human)
C-type lectin domain family 1 member BC-type lectin-like receptor 2; CLEC-2Homo sapiens (human)

Compounds (6)

CompoundDescription
carbon monoxideCarbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
hydroxide ion
hydroxyl radicalThe univalent radical OH. Hydroxyl radical is a potent oxidizing agent.
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.