Page last updated: 2024-10-06

DNA Damage/Telomere Stress Induced Senescence

Proteins (25)

ProteinSynonymsTaxonomy
NibrinCell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Cyclin-dependent kinase 2EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinaseHomo sapiens (human)
Double-strand break repair protein MRE11EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog AHomo sapiens (human)
Protection of telomeres protein 1hPot1; POT1-like telomere end-binding proteinHomo sapiens (human)
Telomeric repeat-binding factor 2TTAGGG repeat-binding factor 2; Telomeric DNA-binding proteinHomo sapiens (human)
Retinoblastoma-associated protein p105-Rb; p110-RB1; pRb; Rb; pp110Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Histone H4Homo sapiens (human)
Serine-protein kinase ATMEC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutatedHomo sapiens (human)
Histone acetyltransferase KAT5EC 2.3.1.48; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting proteinHomo sapiens (human)
Histone chaperone ASF1AAnti-silencing function protein 1 homolog A; hAsf1; hAsf1a; CCG1-interacting factor A; CIA; hCIAHomo sapiens (human)
Telomeric repeat-binding factor 2-interacting protein 1TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homolog; RAP1 homolog; hRap1Homo sapiens (human)
DNA repair protein RAD50hRAD50; EC 3.6.-.-Homo sapiens (human)
E1A-binding protein p400EC 3.6.4.-; CAG repeat protein 32; Domino homolog; hDomino; Trinucleotide repeat-containing gene 12 protein; p400 kDa SWI2/SNF2-related proteinHomo sapiens (human)
High mobility group protein HMG-I/HMG-YHMG-I(Y); High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein RHomo sapiens (human)
Lamin-B1Homo sapiens (human)
High mobility group protein HMGI-CHigh mobility group AT-hook protein 2Homo sapiens (human)
Protein HIRATUP1-like enhancer of split protein 1Homo sapiens (human)
Telomeric repeat-binding factor 1NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1Homo sapiens (human)
Histone H3.1tH3/t; H3t; H3/g; Histone H3.4Homo sapiens (human)
Adrenocortical dysplasia protein homologPOT1 and TIN2-interacting proteinHomo sapiens (human)
TERF1-interacting nuclear factor 2TRF1-interacting nuclear protein 2Homo sapiens (human)
Ubinuclein-1HIRA-binding protein; Protein VT4; Ubiquitously expressed nuclear proteinHomo sapiens (human)
Calcineurin-binding protein cabin-1Calcineurin inhibitor; CAINHomo sapiens (human)

Compounds (4)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.