Pathways > Bile Acid Direct Signalling Pathway (2)
Page last updated: 2024-10-06
Bile Acid Direct Signalling Pathway (2)
Proteins (3)
| Protein | Synonyms | Taxonomy |
|---|
| G-protein coupled bile acid receptor 1 | G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37 | Homo sapiens (human) |
| Glucagon-like peptide 1 receptor | GLP-1 receptor; GLP-1-R; GLP-1R | Homo sapiens (human) |
| Ileal sodium/bile acid cotransporter | Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute | Homo sapiens (human) |
Compounds (2)
| Compound | Description |
|---|
| cholic acid | A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. |
| glucagon-like peptide 1 | A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake. |