Pathways > Antimicrobial peptides
Page last updated: 2024-10-06

Antimicrobial peptides

Proteins (38)

ProteinSynonymsTaxonomy
Neutrophil gelatinase-associated lipocalinNGAL; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin; p25Homo sapiens (human)
Toll-like receptor 1EC 3.2.2.6; Toll/interleukin-1 receptor-like protein; TILHomo sapiens (human)
C-C chemokine receptor type 6C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptorHomo sapiens (human)
DermcidinEC 3.4.-.-; PreproteolysinHomo sapiens (human)
MyeloblastinEC 3.4.21.76; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigenHomo sapiens (human)
C-C chemokine receptor type 2C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-RHomo sapiens (human)
Neutrophil defensin 1Defensin, alpha 1; HNP-1; HP-1; HP1Homo sapiens (human)
T-cell surface glycoprotein CD4T-cell surface antigen T4/Leu-3Homo sapiens (human)
Regenerating islet-derived protein 3-alphaREG-3-alpha; Hepatointestinal pancreatic protein; HIP/PAP; Human proislet peptide; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-alpha; Reg III-alphaHomo sapiens (human)
LactotransferrinLactoferrin; EC 3.4.21.-; Growth-inhibiting protein 12; TalalactoferrinHomo sapiens (human)
Protein S100-A9Calgranulin-B; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; p14; S100 calcium-binding protein A9Homo sapiens (human)
Toll-like receptor 2EC 3.2.2.6; Toll/interleukin-1 receptor-like protein 4Homo sapiens (human)
Envelope glycoprotein gp160Env polyproteinHIV-1 M:B_HXB2R
Phospholipase A2, membrane associatedEC 3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; Non-pancreatic secretory phospholipase A2; NPS-PLA2; Phosphatidylcholine 2-acylhydrolase 2AHomo sapiens (human)
Natural resistance-associated macrophage protein 1NRAMP 1; Solute carrier family 11 member 1Homo sapiens (human)
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono(ADP-ribosyl)transferase 1Homo sapiens (human)
Bactericidal permeability-increasing proteinBPI; CAP 57Homo sapiens (human)
Copper-transporting ATPase 1EC 7.2.2.8; Copper pump 1; Menkes disease-associated proteinHomo sapiens (human)
Peptidoglycan recognition protein 1Peptidoglycan recognition protein short; PGRP-SHomo sapiens (human)
ClusterinAging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Sulfated glycoprotein 2; SGP-2; Testosterone-repressed prostate message 2; TRPM-2Homo sapiens (human)
Lysozyme CEC 3.2.1.17; 1,4-beta-N-acetylmuramidase CHomo sapiens (human)
N-acetylmuramoyl-L-alanine amidaseEC 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-LHomo sapiens (human)
Copper transport protein ATOX1Metal transport protein ATX1Homo sapiens (human)
EppinCancer/testis antigen 71; CT71; Epididymal protease inhibitor; Protease inhibitor WAP7; Serine protease inhibitor-like with Kunitz and WAP domains 1; WAP four-disulfide core domain protein 7Homo sapiens (human)
Semenogelin-1Cancer/testis antigen 103; Semenogelin I; SGIHomo sapiens (human)
Protein S100-A8Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; p8; S100 calcium-binding protein A8; Urinary stone protein band AHomo sapiens (human)
Neutrophil defensin 4Defensin, alpha 4; HNP-4; HP-4Homo sapiens (human)
GranulysinLymphokine LAG-2; Protein NKG5; T-cell activation protein 519Homo sapiens (human)
Cathelicidin antimicrobial peptide18 kDa cationic antimicrobial protein; CAP-18; hCAP-18Homo sapiens (human)
Neutrophil defensin 3Defensin, alpha 3; HNP-3; HP-3; HP3Homo sapiens (human)
Beta-defensin 103Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like proteinHomo sapiens (human)
Defensin-5Defensin, alpha 5; HD5(20-94)Homo sapiens (human)
Defensin-6Defensin, alpha 6Homo sapiens (human)
PDZ domain-containing protein 11ATPase-interacting PDZ protein; Plasma membrane calcium ATPase-interacting single-PDZ protein; PMCA-interacting single-PDZ proteinHomo sapiens (human)
Intelectin-1ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; OmentinHomo sapiens (human)
Liver-expressed antimicrobial peptide 2LEAP-2Homo sapiens (human)
Peptidoglycan recognition protein 4Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate betaHomo sapiens (human)
Peptidoglycan recognition protein 3Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alphaHomo sapiens (human)

Compounds (16)

CompoundDescription
hydronium ion
copperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
carbonatesSalts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
acetylglucosamineThe N-acetyl derivative of glucosamine.
2,5-dihydroxybenzoic acidRN given refers to parent cpd; a oxidative product of saligenin
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
n-acetylmuramic acidRN given refers to D-Glucopyranose, (R)-isomer
lipid II
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