Page last updated: 2024-10-06

1,3-propanediol biosynthesis (engineered)

Proteins (15)

ProteinSynonymsTaxonomy
Fructose-bisphosphate aldolase class 2FBP aldolase; FBPA; EC 4.1.2.13; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class IIEscherichia coli K-12
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1EC 1.1.1.8Saccharomyces cerevisiae S288C
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
Fructose-bisphosphate aldolase class 1EC 4.1.2.13; Fructose-bisphosphate aldolase class I; FBP aldolaseEscherichia coli K-12
ATP-dependent 6-phosphofructokinase subunit alphaEC 2.7.1.11; ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase 1; PhosphohexokinaseSaccharomyces cerevisiae S288C
ATP-dependent 6-phosphofructokinase subunit betaEC 2.7.1.11; ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase 2; PhosphohexokinaseSaccharomyces cerevisiae S288C
Phosphocarrier protein HPrHistidine-containing proteinEscherichia coli K-12
GlucokinaseEC 2.7.1.2; Glucose kinaseEscherichia coli K-12
ATP-dependent 6-phosphofructokinase isozyme 2ATP-PFK 2; Phosphofructokinase 2; EC 2.7.1.11; 6-phosphofructokinase isozyme II; Phosphohexokinase 2Escherichia coli K-12
ATP-dependent 6-phosphofructokinase isozyme 1ATP-PFK 1; Phosphofructokinase 1; EC 2.7.1.11; 6-phosphofructokinase isozyme I; Phosphohexokinase 1Escherichia coli K-12
Galactose-proton symporterGalactose transporterEscherichia coli K-12
Alcohol dehydrogenase YqhDEC 1.1.1.-Escherichia coli K-12
DhaC protein Klebsiella pneumoniae
Glycerol dehydrase alpha subunit Klebsiella pneumoniae
Glycerol dehydrase gamma subunit Klebsiella pneumoniae

Compounds (27)

CompoundDescription
hydronium ion
SilverAn element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
NADH
Ammonium
MercuryA silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
serum p-componentclose relation to C reactive protein; may be ovosomucoid
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
GlucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
glycerolA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NickelA trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
cobamamide
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Edetic AcidA chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
fructose-1,6-diphosphateRN refers to (D)-isomer
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
alpha-glycerophosphoric acid
1,3-propanediol
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
reuterin