Page last updated: 2024-09-05

vx-745 and vk 19911

vx-745 has been researched along with vk 19911 in 2 studies

Compound Research Comparison

Studies
(vx-745)
Trials
(vx-745)
Recent Studies (post-2010)
(vx-745)
Studies
(vk 19911)
Trials
(vk 19911)
Recent Studies (post-2010) (vk 19911)
58135501

Protein Interaction Comparison

ProteinTaxonomyvx-745 (IC50)vk 19911 (IC50)
Mitogen-activated protein kinase 13Homo sapiens (human)0.1216
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.038
Mitogen-activated protein kinase 12Homo sapiens (human)0.1216
Mitogen-activated protein kinase 11Homo sapiens (human)0.1216
Mitogen-activated protein kinase 14Homo sapiens (human)0.1009

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aaes, H; Binderup, L; Björkling, F; Fjording, MS; Ottosen, ER; Skak-Nielsen, T; Sørensen, MD1
Bellon, SF; Bemis, GW; Chen, G; Cochran, JE; Duffy, JP; Evindar, G; Ford, PJ; Galullo, VP; Gao, H; Germann, UA; Green, J; Harrington, EM; Huang, C; Jones, P; Murcko, MA; Pazhanisamy, S; Salituro, FG; Su, MS; Taslimi, P; Wang, YM; Wilson, KP1

Other Studies

2 other study(ies) available for vx-745 and vk 19911

ArticleYear
Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Dermatitis, Contact; Female; Humans; In Vitro Techniques; Interleukin-1; Interleukin-2; Leukocytes, Mononuclear; Ligands; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Peroxidase; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2003
The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.
    ACS medicinal chemistry letters, 2011, Oct-13, Volume: 2, Issue:10

    Topics:

2011