vx-745 has been researched along with sk&f 86002 in 2 studies
| Studies (vx-745) | Trials (vx-745) | Recent Studies (post-2010) (vx-745) | Studies (sk&f 86002) | Trials (sk&f 86002) | Recent Studies (post-2010) (sk&f 86002) |
|---|---|---|---|---|---|
| 58 | 1 | 35 | 83 | 4 | 13 |
| Protein | Taxonomy | vx-745 (IC50) | sk&f 86002 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 3.8 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 5.4 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 10 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 3.8 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 3.8 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 2.1217 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Laufer, S; Wagner, G | 1 |
1 review(s) available for vx-745 and sk&f 86002
| Article | Year |
|---|---|
Small molecular anti-cytokine agents.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Caspase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytokines; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridazines; Pyridines; Pyrimidines; Quinazolines; Structure-Activity Relationship; Succinates; Thiazoles; Tumor Necrosis Factor-alpha; Urea | 2006 |
1 other study(ies) available for vx-745 and sk&f 86002
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |