Page last updated: 2024-09-05

vx-745 and sb 239063

vx-745 has been researched along with sb 239063 in 2 studies

Compound Research Comparison

Studies
(vx-745)
Trials
(vx-745)
Recent Studies (post-2010)
(vx-745)
Studies
(sb 239063)
Trials
(sb 239063)
Recent Studies (post-2010) (sb 239063)
5813584035

Protein Interaction Comparison

ProteinTaxonomyvx-745 (IC50)sb 239063 (IC50)
Mitogen-activated protein kinase 13Homo sapiens (human)0.044
Epidermal growth factor receptorHomo sapiens (human)0.083
Tyrosine-protein kinase LckHomo sapiens (human)0.018
Protein kinase C alpha typeHomo sapiens (human)0.083
Mitogen-activated protein kinase 9Homo sapiens (human)0.005
Mitogen-activated protein kinase 12Homo sapiens (human)0.044
Mitogen-activated protein kinase 11Homo sapiens (human)0.044
Mitogen-activated protein kinase 14Homo sapiens (human)0.0415

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Bajić, M; Bistrović, A; Grbčić, P; Harej, A; Koštrun, S; Krstulović, L; Pavelić, SK; Raić-Malić, S; Sedić, M1

Other Studies

2 other study(ies) available for vx-745 and sb 239063

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Amidines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship; Triazoles

2018