tak 044 and pd 98059
tak 044 has been researched along with pd 98059 in 2 studies
Compound Research Comparison
| Studies (tak 044) | Trials (tak 044) | Recent Studies (post-2010) (tak 044) | Studies (pd 98059) | Trials (pd 98059) | Recent Studies (post-2010) (pd 98059) |
|---|---|---|---|---|---|
| 105 | 8 | 2 | 4,939 | 3 | 1,001 |
Protein Interaction Comparison
| Protein | Taxonomy | tak 044 (IC50) | pd 98059 (IC50) |
|---|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 2.8 | |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | 6.3 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 2.8 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 2.8 | |
| Dual specificity mitogen-activated protein kinase kinase 2 | Rattus norvegicus (Norway rat) | 4.2 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Rattus norvegicus (Norway rat) | 4.2 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 2.4 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T | 1 |
| Fukai, N; Hirata, Y; Ozawa, N; Sato, R; Shichiri, M; Sugiyama, T; Yoshimoto, T | 1 |
Other Studies
2 other study(ies) available for tak 044 and pd 98059
| Article | Year |
|---|---|
Lysophosphatidylcholine is a major contributor to the synergistic effect of mildly oxidized low-density lipoprotein with endothelin-1 on vascular smooth muscle cell proliferation.
Topics: Acetylcysteine; Aldehydes; Animals; Aorta, Thoracic; Cell Count; Cell Division; Cells, Cultured; DNA; Endothelin Receptor Antagonists; Endothelin-1; Flavonoids; Free Radical Scavengers; Growth Inhibitors; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Oxidants; Peptides, Cyclic; Rabbits; Reactive Oxygen Species | 2002 |
Endothelin-1 induces cyclooxygenase-2 expression and generation of reactive oxygen species in endothelial cells.
Topics: Aldosterone; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endothelial Cells; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Induction; Flavonoids; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Peptides, Cyclic; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Endothelin; RNA, Messenger; Sulfonamides | 2004 |