Page last updated: 2024-09-03

sgb 1534 and ketanserin

sgb 1534 has been researched along with ketanserin in 3 studies

Compound Research Comparison

Studies
(sgb 1534)
Trials
(sgb 1534)
Recent Studies (post-2010)
(sgb 1534)
Studies
(ketanserin)
Trials
(ketanserin)
Recent Studies (post-2010) (ketanserin)
20003,094335283

Protein Interaction Comparison

ProteinTaxonomysgb 1534 (IC50)ketanserin (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0021
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.015
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.015
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.265
5-hydroxytryptamine receptor 1BHomo sapiens (human)6.5
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0184
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0027
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.29
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.015
D(2) dopamine receptorRattus norvegicus (Norway rat)1.8
Synaptic vesicular amine transporterHomo sapiens (human)0.18
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.001

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagatomo, T; Tsuchihashi, H1
Aono, J; Ishizuka, N; Nabata, H; Sakai, K1
Aono, J; Hokibara, R; Nagatomo, T; Nakamura, T; Tanaka, Y; Tsuchihashi, H1

Other Studies

3 other study(ies) available for sgb 1534 and ketanserin

ArticleYear
Alpha-blocking potencies of antihypertensive agents (prazosin, terazosin, bunazosin, SGB-1534 and ketanserin) having with quinazoline or quinazolinedione as assessed by radioligand binding assay methods in rat brain.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brain; Cell Membrane; Clonidine; Dihydroalprenolol; Ketanserin; Male; Prazosin; Quinazolines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1989
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Decerebrate State; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Piperidines; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Serotonin Antagonists

1985
Effects of ketanserin and 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monohydrochloride (SGB-1534), anti-hypertensive agents, on 3H-serotonin and 3H-ketanserin bindings to serotonergic (5HT1 and 5HT2) receptors in dog brain
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Brain Chemistry; Dogs; Female; In Vitro Techniques; Ketanserin; Male; Muscle, Smooth, Vascular; Quinazolines; Receptors, Serotonin; Serotonin

1988