pd 142893 and ro 46-2005
pd 142893 has been researched along with ro 46-2005 in 4 studies
Compound Research Comparison
| Studies (pd 142893) | Trials (pd 142893) | Recent Studies (post-2010) (pd 142893) | Studies (ro 46-2005) | Trials (ro 46-2005) | Recent Studies (post-2010) (ro 46-2005) |
|---|---|---|---|---|---|
| 64 | 0 | 3 | 26 | 0 | 1 |
Protein Interaction Comparison
| Protein | Taxonomy | pd 142893 (IC50) | ro 46-2005 (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | 1 | |
| Endothelin receptor type B | Homo sapiens (human) | 1.1 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.22 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.23 | |
| Endothelin-1 receptor | Sus scrofa (pig) | 0.16 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chiou, WJ; Magnuson, SR; Opgenorth, TJ; Wu-Wong, JR | 1 |
| Battistini, B; Corder, R; Doherty, AM; Warner, TD | 1 |
| Chiou, WJ; Naugles, KE; Opgenorth, TJ; Wu-Wong, JR | 1 |
| Chiou, WJ; Dixon, D; Magnuson, SR; Opgenorth, TJ; Sundy, S; Wu-Wong, JR | 1 |
Reviews
1 review(s) available for pd 142893 and ro 46-2005
| Article | Year |
|---|---|
Endothelin receptor antagonists: actions and rationale for their development.
Topics: Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Disease Models, Animal; Drug Design; Endothelin Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Humans; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides | 1994 |
Other Studies
3 other study(ies) available for pd 142893 and ro 46-2005
| Article | Year |
|---|---|
Endothelin receptor agonists and antagonists exhibit different dissociation characteristics.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain Chemistry; CHO Cells; Cricetinae; Endothelin Receptor Antagonists; Endothelins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pyrimidines; Receptors, Endothelin; Sulfonamides; Swine | 1994 |
Endothelin receptor antagonists exhibit diminishing potency following incubation with agonist.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Endothelin Receptor Antagonists; Endothelins; Molecular Sequence Data; Oligopeptides; Pyrimidines; Radioligand Assay; Receptors, Endothelin; Sulfonamides; Swine | 1994 |
Dissociation characteristics of endothelin receptor agonists and antagonists in cloned human type-B endothelin receptor.
Topics: Animals; CHO Cells; Cricetinae; Endothelin Receptor Antagonists; Endothelins; Humans; Kinetics; Molecular Weight; Oligopeptides; Peptide Fragments; Protein Binding; Pyrimidines; Receptor, Endothelin B; Receptors, Endothelin; Recombinant Fusion Proteins; Sulfonamides | 1997 |