Page last updated: 2024-09-03

pd 142893 and ro 46-2005

pd 142893 has been researched along with ro 46-2005 in 4 studies

Compound Research Comparison

Studies
(pd 142893)
Trials
(pd 142893)
Recent Studies (post-2010)
(pd 142893)
Studies
(ro 46-2005)
Trials
(ro 46-2005)
Recent Studies (post-2010) (ro 46-2005)
64032601

Protein Interaction Comparison

ProteinTaxonomypd 142893 (IC50)ro 46-2005 (IC50)
Endothelin receptor type BRattus norvegicus (Norway rat)1
Endothelin receptor type BHomo sapiens (human)1.1
Endothelin-1 receptorHomo sapiens (human)0.22
Endothelin-1 receptorRattus norvegicus (Norway rat)0.23
Endothelin-1 receptorSus scrofa (pig)0.16

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiou, WJ; Magnuson, SR; Opgenorth, TJ; Wu-Wong, JR1
Battistini, B; Corder, R; Doherty, AM; Warner, TD1
Chiou, WJ; Naugles, KE; Opgenorth, TJ; Wu-Wong, JR1
Chiou, WJ; Dixon, D; Magnuson, SR; Opgenorth, TJ; Sundy, S; Wu-Wong, JR1

Reviews

1 review(s) available for pd 142893 and ro 46-2005

ArticleYear
Endothelin receptor antagonists: actions and rationale for their development.
    Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Disease Models, Animal; Drug Design; Endothelin Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Humans; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides

1994

Other Studies

3 other study(ies) available for pd 142893 and ro 46-2005

ArticleYear
Endothelin receptor agonists and antagonists exhibit different dissociation characteristics.
    Biochimica et biophysica acta, 1994, Nov-10, Volume: 1224, Issue:2

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain Chemistry; CHO Cells; Cricetinae; Endothelin Receptor Antagonists; Endothelins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Pyrimidines; Receptors, Endothelin; Sulfonamides; Swine

1994
Endothelin receptor antagonists exhibit diminishing potency following incubation with agonist.
    Life sciences, 1994, Volume: 54, Issue:22

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Endothelin Receptor Antagonists; Endothelins; Molecular Sequence Data; Oligopeptides; Pyrimidines; Radioligand Assay; Receptors, Endothelin; Sulfonamides; Swine

1994
Dissociation characteristics of endothelin receptor agonists and antagonists in cloned human type-B endothelin receptor.
    Endothelium : journal of endothelial cell research, 1997, Volume: 5, Issue:3

    Topics: Animals; CHO Cells; Cricetinae; Endothelin Receptor Antagonists; Endothelins; Humans; Kinetics; Molecular Weight; Oligopeptides; Peptide Fragments; Protein Binding; Pyrimidines; Receptor, Endothelin B; Receptors, Endothelin; Recombinant Fusion Proteins; Sulfonamides

1997
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