Page last updated: 2024-09-05

orantinib and mln8054

orantinib has been researched along with mln8054 in 3 studies

Compound Research Comparison

Studies
(orantinib)
Trials
(orantinib)
Recent Studies (post-2010)
(orantinib)
Studies
(mln8054)
Trials
(mln8054)
Recent Studies (post-2010) (mln8054)
110193661342
80761342

Protein Interaction Comparison

ProteinTaxonomyorantinib (IC50)mln8054 (IC50)
Aurora kinase AHomo sapiens (human)0.0398
Aurora kinase BMus musculus (house mouse)0.172
Tyrosine-protein kinase LckHomo sapiens (human)3.2
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)0.33
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.7943
Aurora kinase AMus musculus (house mouse)0.0085
Aurora kinase BHomo sapiens (human)1.6916
Aurora kinase CHomo sapiens (human)0.0118

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhatt, HG; Borisa, AC1
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1

Reviews

1 review(s) available for orantinib and mln8054

ArticleYear
A comprehensive review on Aurora kinase: Small molecule inhibitors and clinical trial studies.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Animals; Antineoplastic Agents; Aurora Kinases; Cell Proliferation; Clinical Trials as Topic; Humans; Molecular Structure; Protein Kinase Inhibitors; Small Molecule Libraries

2017

Other Studies

2 other study(ies) available for orantinib and mln8054

ArticleYear
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011