Page last updated: 2024-09-03

ly 163443 and fpl 55712

ly 163443 has been researched along with fpl 55712 in 4 studies

Compound Research Comparison

Studies
(ly 163443)
Trials
(ly 163443)
Recent Studies (post-2010)
(ly 163443)
Studies
(fpl 55712)
Trials
(fpl 55712)
Recent Studies (post-2010) (fpl 55712)
100039323

Protein Interaction Comparison

ProteinTaxonomyly 163443 (IC50)fpl 55712 (IC50)
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.58
Bile salt export pumpHomo sapiens (human)10
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.51
Thromboxane-A synthase Homo sapiens (human)10
Cysteinyl leukotriene receptor 2Homo sapiens (human)0.51
Cysteinyl leukotriene receptor 1Homo sapiens (human)2.255

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krell, RD; Shaw, A1
Carr, FP; Dillard, RD; Fleisch, JH; Haisch, KD; McCullough, D; Rinkema, LE1
Denzlinger, C; Grimberg, M; Haberl, C; Kapp, A; Wilmanns, W1
Cloud, ML; Fleisch, JH; Marshall, WS1

Reviews

2 review(s) available for ly 163443 and fpl 55712

ArticleYear
Peptide leukotrienes: current status of research.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Acetophenones; Humans; Leukotriene Antagonists; Leukotrienes; Molecular Structure; Peptides; Receptors, Immunologic; Receptors, Leukotriene; Tetrazoles

1991
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
    Annals of the New York Academy of Sciences, 1988, Volume: 524

    Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles

1988

Other Studies

2 other study(ies) available for ly 163443 and fpl 55712

ArticleYear
Leukotriene receptor antagonists. 2. The [[(tetrazol-5-ylaryl)oxy]methyl]acetophenone derivatives.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Acetophenones; Animals; Azoles; Bronchi; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea

1987
Effect of the leukotriene receptor antagonists FPL 55712, LY 163443, and MK-571 on the elimination of cysteinyl leukotrienes in the rat.
    British journal of pharmacology, 1991, Volume: 102, Issue:4

    Topics: Acetophenones; Animals; Bile; Chromatography, High Pressure Liquid; Chromones; Leukotrienes; Male; Propionates; Quinolines; Radioimmunoassay; Rats; Rats, Inbred Strains; SRS-A

1991