l 778,123 has been researched along with fti 276 in 3 studies
| Studies (l 778,123) | Trials (l 778,123) | Recent Studies (post-2010) (l 778,123) | Studies (fti 276) | Trials (fti 276) | Recent Studies (post-2010) (fti 276) |
|---|---|---|---|---|---|
| 23 | 3 | 2 | 30 | 0 | 13 |
| 15 | 0 | 5 | 30 | 0 | 13 |
| Protein | Taxonomy | l 778,123 (IC50) | fti 276 (IC50) |
|---|---|---|---|
| Protein farnesyltransferase subunit beta | Saccharomyces cerevisiae S288C | 0.0008 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Bos taurus (cattle) | 0.0005 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Saccharomyces cerevisiae S288C | 0.0008 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.0067 | |
| Protein farnesyltransferase subunit beta | Bos taurus (cattle) | 0.0005 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.0033 | |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | 0.05 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Mus musculus (house mouse) | 1 | |
| Protein farnesyltransferase subunit beta | Mus musculus (house mouse) | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamilton, AD; Kastens, E; Lantry, LE; Liu, G; Lubet, RA; Sebti, SM; Wang, Y; You, M; Zhang, Z | 1 |
| Bell, IM | 1 |
| Distefano, MD; Ochocki, JD | 1 |
1 review(s) available for l 778,123 and fti 276
| Article | Year |
|---|---|
Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Design; Farnesyltranstransferase; Genes, ras; Humans; Neoplasms | 2004 |
2 other study(ies) available for l 778,123 and fti 276
| Article | Year |
|---|---|
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Anticarcinogenic Agents; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Inhibitors; Farnesyltranstransferase; Gene Deletion; Genes, Dominant; Genes, p53; Heterozygote; Imidazoles; Lung Neoplasms; Methionine; Mice; Mice, Inbred A; Mice, Knockout; Mice, Transgenic | 2003 |
Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.
Topics: | 2013 |