Page last updated: 2024-09-03

gefitinib and naringenin

gefitinib has been researched along with naringenin in 2 studies

Compound Research Comparison

Studies (gefitinib)	Trials (gefitinib)	Recent Studies (post-2010) (gefitinib)	Studies (naringenin)	Trials (naringenin)	Recent Studies (post-2010) (naringenin)
5,231	566	2,919	1,578	22	1,055

Protein Interaction Comparison

Protein	Taxonomy	naringenin (IC50)
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Chain A, Mitogen-activated protein kinase 14	Homo sapiens (human)	292
Cytochrome P450 3A4	Homo sapiens (human)	3.3
Cytochrome P450 2D6	Homo sapiens (human)	3.3
Aromatase	Homo sapiens (human)	1.3881
Cytochrome P450 2C9	Homo sapiens (human)	3.3
17-beta-hydroxysteroid dehydrogenase type 1	Homo sapiens (human)	4.96
Dipeptidyl peptidase 4	Homo sapiens (human)	0.24
Cytochrome P450 1B1	Homo sapiens (human)	3.656
Integrase	Human immunodeficiency virus 1	1.7

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Arya, M; Guleria, A; Kanoujia, J; Kumar, A; Parashar, P; Saraf, SA; Singh, M; Tripathi, CB; Yadav, A	1

Other Studies

2 other study(ies) available for gefitinib and naringenin

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Biotinylated naringenin intensified anticancer effect of gefitinib in urethane-induced lung cancer in rats: favourable modulation of apoptotic regulators and serum metabolomics. Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup3 Topics: A549 Cells; Animals; Apoptosis Regulatory Proteins; Drug Screening Assays, Antitumor; Female; Flavanones; Gefitinib; Humans; Lung Neoplasms; Male; Metabolomics; Neoplasm Proteins; Rats; Rats, Wistar; Urethane	2018

Article

Year

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008

Biotinylated naringenin intensified anticancer effect of gefitinib in urethane-induced lung cancer in rats: favourable modulation of apoptotic regulators and serum metabolomics.

Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup3

Topics: A549 Cells; Animals; Apoptosis Regulatory Proteins; Drug Screening Assays, Antitumor; Female; Flavanones; Gefitinib; Humans; Lung Neoplasms; Male; Metabolomics; Neoplasm Proteins; Rats; Rats, Wistar; Urethane

2018