etravirine and indinavir sulfate
etravirine has been researched along with indinavir sulfate in 5 studies
Compound Research Comparison
Studies (etravirine) | Trials (etravirine) | Recent Studies (post-2010) (etravirine) | Studies (indinavir sulfate) | Trials (indinavir sulfate) | Recent Studies (post-2010) (indinavir sulfate) |
---|---|---|---|---|---|
572 | 90 | 321 | 1,834 | 328 | 146 |
Protein Interaction Comparison
Protein | Taxonomy | etravirine (IC50) | indinavir sulfate (IC50) |
---|---|---|---|
Gag-Pol polyprotein | Human immunodeficiency virus type 1 (BRU ISOLATE) | 0.0004 | |
Gag polyprotein | HIV-1 M:B_MN | 0.02 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 0.2 | |
Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.0261 | |
Substance-K receptor | Homo sapiens (human) | 5.101 | |
Thromboxane-A synthase | Homo sapiens (human) | 1.851 | |
Protease | Human immunodeficiency virus 1 | 0.0349 | |
Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 7.8 | |
Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 3.8 | |
Protease | Human immunodeficiency virus 1 | 0.0044 |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 2 (40.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Corbau, R; Fishburn, L; Irving, S; Knöchel, T; Martin, A; Mori, J; Mowbray, C; Panton, W; Perros, M; Phillips, C; Ringrose, H; Smith-Burchnell, C; Thornberry, A; Westby, M; Wood, A | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Danner, SA; Gruzdev, B; Jurriaans, S; Lange, JM; Peeters, M; Prins, JM; Rakhmanova, A; Sankatsing, SU; van't Klooster, G; Weverling, GJ | 1 |
Al-Dhabi, NA; Arunagirinathan, N; Ignacimuthu, S; Indu, P; Rameshkumar, MR; Valan Arasu, M | 1 |
Reviews
1 review(s) available for etravirine and indinavir sulfate
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Trials
1 trial(s) available for etravirine and indinavir sulfate
Article | Year |
---|---|
TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2003 |
Other Studies
3 other study(ies) available for etravirine and indinavir sulfate
Article | Year |
---|---|
Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.
Topics: Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitriles; Pyrazoles; Reverse Transcriptase Inhibitors | 2010 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach.
Topics: Antiviral Agents; Coronavirus Protease Inhibitors; COVID-19 Drug Treatment; Drug Repositioning; Heterocyclic Compounds, 3-Ring; Humans; Indinavir; Molecular Docking Simulation; Nitriles; Oxazines; Piperazines; Pyridines; Pyridones; Pyrimidines; Pyrones; Raltegravir Potassium; RNA-Dependent RNA Polymerase; SARS-CoV-2; Sulfonamides | 2020 |