emd 53998 has been researched along with dobutamine in 7 studies
| Studies (emd 53998) | Trials (emd 53998) | Recent Studies (post-2010) (emd 53998) | Studies (dobutamine) | Trials (dobutamine) | Recent Studies (post-2010) (dobutamine) |
|---|---|---|---|---|---|
| 112 | 0 | 9 | 6,357 | 818 | 1,011 |
| Protein | Taxonomy | emd 53998 (IC50) | dobutamine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 4.17 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 5.551 | |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | 5.519 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 3.975 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 1.517 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.383 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 1.944 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.599 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 2.966 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.383 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.114 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 1.895 | |
| D(3) dopamine receptor | Homo sapiens (human) | 4.985 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.155 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 2.518 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DelNido, PJ; Grandis, DJ; Koretsky, AP | 1 |
| Campbell, KB; Green, HW; Kirkpatrick, RD; Slinker, BK; Wu, Y | 2 |
| Ekelund, U; Hare, JM; Isoda, T; Kass, DA; Paolocci, N; Senzaki, H | 1 |
| Atsumi, H; Endoh, M; Nakada, S; Sakurai, K; Sugawara, H; Tomoike, H | 1 |
| Krams, R; Slager, CJ; Smits, CA; Trines, SA; van der Moer, J; Verdouw, PD | 1 |
| Allessie, M; Blaauw, Y; de Haan, S; Greiser, M; Harks, E; Schotten, U; van Hunnik, A; Verheule, S | 1 |
7 other study(ies) available for emd 53998 and dobutamine
| Article | Year |
|---|---|
Functional and energetic effects of the inotropic agents EMD-57033 and BAPTA on the isolated rat heart.
Topics: Animals; Cardiotonic Agents; Dobutamine; Egtazic Acid; Energy Metabolism; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphorus; Quinolines; Rats; Rats, Sprague-Dawley; Thiadiazines; Verapamil | 1995 |
Relaxation effect of CGP-48506, EMD-57033, and dobutamine in ejecting and isovolumically beating rabbit hearts.
Topics: Animals; Azocines; Cardiotonic Agents; Dobutamine; Heart; Heart Rate; In Vitro Techniques; Male; Mathematics; Models, Cardiovascular; Myocardial Contraction; Quinolines; Rabbits; Regression Analysis; Stroke Volume; Thiadiazines; Vasodilation | 1997 |
Improved mechanoenergetics and cardiac rest and reserve function of in vivo failing heart by calcium sensitizer EMD-57033.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output, Low; Cardiotonic Agents; Coronary Circulation; Diastole; Dobutamine; Dogs; Female; Heart; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Quinolines; Rest; Thiadiazines | 2000 |
Overall cardiac functional effect of positive inotropic drugs with differing effects on relaxation.
Topics: Animals; Azocines; Calcium; Cardiac Output; Cardiotonic Agents; Dobutamine; Heart Rate; Male; Quinolines; Rabbits; Stroke Volume; Thiadiazines; Ventricular Function, Left | 2000 |
Differential alteration of cardiotonic effects of EMD 57033 and beta-adrenoceptor agonists in volume-overload rabbit ventricular myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Drug Evaluation, Preclinical; Electrocardiography; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Contraction; Myofibrils; Phosphodiesterase Inhibitors; Quinolines; Rabbits; Thiadiazines | 2000 |
Calcium sensitizer EMD 57033, but not the beta1-adrenoreceptor agonist dobutamine, increases mechanical efficiency in stunned myocardium.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Dobutamine; Energy Metabolism; Heart; Hemodynamics; Myocardial Contraction; Myocardial Stunning; Oxygen Consumption; Quinolines; Stimulation, Chemical; Swine; Thiadiazines | 2002 |
AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat.
Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Function, Right; Biphenyl Compounds; Cardiotonic Agents; Delayed Rectifier Potassium Channels; Digoxin; Dihydropyridines; Disease Models, Animal; Dobutamine; Electric Countershock; Electrocardiography; Goats; Myocardial Contraction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinolines; Thiadiazines | 2006 |