e 5110 has been researched along with kme 4 in 3 studies
| Studies (e 5110) | Trials (e 5110) | Recent Studies (post-2010) (e 5110) | Studies (kme 4) | Trials (kme 4) | Recent Studies (post-2010) (kme 4) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 13 | 0 | 0 |
| Protein | Taxonomy | e 5110 (IC50) | kme 4 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 1.1 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 2.62 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.11 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.11 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 1.3625 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 1.3625 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belliotti, TR; Boctor, AM; Connor, DT; Flynn, DL; Kostlan, CR; Nies, DE; Ortwine, DF; Schrier, DJ; Sircar, JC | 1 |
| Cetenko, WA; Connor, DT; Dyer, RD; Kostlan, CR; Schrier, DJ; Sircar, JC; Sorenson, RJ; Unangst, PC; Wright, CD | 1 |
| Connor, DT; Dyer, RD; Kostlan, CR; Mullican, MD; Schrier, DJ; Wilson, MW | 1 |
3 other study(ies) available for e 5110 and kme 4
| Article | Year |
|---|---|
Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.
Topics: Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Isoxazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pyrazoles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles | 1991 |
Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)- 4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Imidazoles; Lipoxygenase Inhibitors; Oxazoles; Rats; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 1994 |
Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Imidazoles; Lipoxygenase Inhibitors; Male; Oxadiazoles; Rats; Rats, Wistar; Thiadiazoles; Triazoles | 1993 |