Compounds > cyc 202
Page last updated: 2024-09-04

cyc 202 and h 89

cyc 202 has been researched along with h 89 in 6 studies

Compound Research Comparison

Studies
(cyc 202)		Trials
(cyc 202)		Recent Studies (post-2010)
(cyc 202)		Studies
(h 89)		Trials
(h 89)		Recent Studies (post-2010) (h 89)
97973931,6190409

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)h 89 (IC50)
Rho-associated protein kinase 2Homo sapiens (human)1.9504
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.12
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.073
cAMP-dependent protein kinase catalytic subunit alpha Mus musculus (house mouse)0.381
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)0.6365
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)0.6365
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)0.6365
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.08
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)1.9886
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)0.5417
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)0.27
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)0.3207

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Abdali, SA; Bakshi, K; Friedman, E; Gil, M; Goswami, S; Zhen, X1
Chen, F; Lin, J; Ning, SF; Sun, X; Tan, JH; Wang, HL; Xiao, B; Zhu, S1

Other Studies

6 other study(ies) available for cyc 202 and h 89

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Regulation of cyclin-dependent kinase 5 and calcium/calmodulin-dependent protein kinase II by phosphatidylinositol-linked dopamine receptor in rat brain.
    Molecular pharmacology, 2004, Volume: 66, Issue:6

    Topics: Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; Isoquinolines; Kinetics; Nerve Tissue Proteins; Phosphatidylinositols; Phosphorylation; Purines; Rats; Receptors, Dopamine; Roscovitine; Sulfonamides

2004
Mechanisms by which in vitro meiotic arrest and sexual maturity improve developmental potential of mouse oocytes.
    Scientific reports, 2017, Nov-17, Volume: 7, Issue:1

    Topics: Alpha-Amanitin; Animals; Bucladesine; Cell Cycle Checkpoints; Cell Nucleolus; Chromatin; Cumulus Cells; Cyclin-Dependent Kinase 5; Cytoplasm; Embryonic Development; Female; Isoquinolines; Meiosis; Mice; Oocytes; RNA; RNA Polymerase II; Roscovitine; Sexual Maturation; Sulfonamides; Transcription, Genetic

2017