Page last updated: 2024-09-05

biotin and thyroxine

biotin has been researched along with thyroxine in 31 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(thyroxine)
Trials
(thyroxine)
Recent Studies (post-2010) (thyroxine)
14,847953,88238,9891,4106,550

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)thyroxine (IC50)
TransthyretinHomo sapiens (human)2.1939
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)5.25
Solute carrier organic anion transporter family member 4C1Homo sapiens (human)8
Bile acid receptorHomo sapiens (human)7.86

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's7 (22.58)18.2507
2000's1 (3.23)29.6817
2010's12 (38.71)24.3611
2020's8 (25.81)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bryden, WL1
Bhayana, V; Diamandis, EP; Papanastasiou-Diamandis, A1
Bhuvaneswaran, C; Dakshinamurti, K1
Akman, S; Karaca, L; Kutluay, T1
Khosravi, MJ; Papanastasiou-Diamandi, A1
Fukui, T; Mori, M; Nagamine, T; Takehara, K1
Arafat, N; Henry, JG; Sobki, S1
Ito, Y1
Adamczyk, M; Fishpaugh, JR; Mattingly, PG1
Han, SQ; He, YF; Wu, FB1
Jochum, FD; Roth, PJ; Theato, P; Zentel, R1
Duan, X; Huskens, J; Rajan, NK; Reed, MA; Routenberg, DA1
Cardamone, D; Master, SR; Rulander, NJ; Senior, M; Snyder, PJ1
Barbesino, G1
Endert, E; Mijnhout, GS; Rondeel, JMM; Vos, MJ1
Decoudier, B; Delemer, B; Maquart, FX; Marot, D1
Basit, A; Emanuele, MA; Emanuele, N; Holmes, EW; Mazhari, A; Meah, F; Samarasinghe, S; Singh, V1
Guteneva, NV; Lunin, AV; Mochalova, EN; Nikitin, MP; Nikitin, PI; Orlov, AV; Pushkarev, AV; Znoyko, SL1
Bourgeois, L; Dasgupta, A1
de Heide, LJM; Lutgers, HL; Slim, CL; van den Berg, R; Wolthuis, A1
Burniat, A; Cotton, F; Fage, D; Mathieu, E; Ruth, I; Wolff, F1
Agudo-Macazaga, M; Lorenzo-Lozano, MC; Rodríguez González, D; Ruiz-Ginés, JA; Ruiz-Ginés, MÁ1
Benavides, R; Bowen, R; Colón-Franco, JM; Katzman, BM; Klause, U; Muthukumar, A; Sadrzadeh, H; Straseski, J; Tran, N1
Choi, J; Yun, SG1
Dong, Y; Huang, G; Ji, B; Wang, Q; Wang, R; Zhang, Y1
Abu Rous, F; Aldasouqi, S; Alratroot, A; Lundin, MS1
A Gold, K; C Barnachea, L; N Ridgway, F1
Dasgupta, A; McBride, M1
Emoto, M; Fujiwara, N; Hamaoka, A; Inami, M; Kamei, N; Morioka, T; Shimmaru, K1

Reviews

2 review(s) available for biotin and thyroxine

ArticleYear
BIOTIN INTERFERENCE WITH ROUTINE CLINICAL IMMUNOASSAYS: UNDERSTAND THE CAUSES AND MITIGATE THE RISKS.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:8

    Topics: Biotin; Drug Interactions; Estradiol; Follicle Stimulating Hormone; Hormones; Humans; Hydrocortisone; Immunoassay; Indicators and Reagents; Luteinizing Hormone; Parathyroid Hormone; Progesterone; Prolactin; Streptavidin; Thyroid Function Tests; Thyrotropin; Thyroxine

2017
Best practices in mitigating the risk of biotin interference with laboratory testing.
    Clinical biochemistry, 2019, Volume: 74

    Topics: Adult; Aged; Aged, 80 and over; Awareness; Biotin; Child; Child, Preschool; Diagnostic Errors; Dietary Supplements; Female; Graves Disease; Humans; Immunoassay; Infant; Infant, Newborn; Laboratories; Male; Medical Laboratory Personnel; Medical Staff; Middle Aged; Patient Education as Topic; Practice Guidelines as Topic; Thyroid Function Tests; Thyrotropin; Thyroxine

2019

Other Studies

29 other study(ies) available for biotin and thyroxine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Modulation of plasma biotin in the fowl (Gallus domesticus) by oestrogen and ambient temperature.
    Comparative biochemistry and physiology. A, Comparative physiology, 1991, Volume: 98, Issue:2

    Topics: Animals; Biotin; Chickens; Egg Yolk; Estrogens; Female; Hot Temperature; Thyroxine; Triiodothyronine

1991
A simple time-resolved fluoroimmunoassay of total thyroxine in serum.
    Annals of clinical biochemistry, 1989, Volume: 26 ( Pt 3)

    Topics: Bacterial Proteins; Biotin; Cross Reactions; Evaluation Studies as Topic; Fluorescent Dyes; Fluoroimmunoassay; Phenanthrolines; Streptavidin; Thyroxine

1989
Energy-linked swelling of biotin-deficient rat liver mitochondria.
    Archives of biochemistry and biophysics, 1971, Volume: 142, Issue:2

    Topics: Animals; Antimycin A; Biotin; Hydroxybutyrates; Male; Microscopy, Electron; Mitochondria, Liver; Mitochondrial Swelling; NAD; Oxidative Phosphorylation; Oxidoreductases; Phosphates; Polarography; Rats; Spectrophotometry; Succinates; Thyroxine; Ubiquinone; Vitamin B Deficiency

1971
An enzymeimmunoassay for total thyroxine using avidin-biotin separation system and thyroxine-peroxidase conjugate.
    Journal of immunoassay, 1995, Volume: 16, Issue:3

    Topics: Animals; Avidin; Biotin; Chromatography, Affinity; Horseradish Peroxidase; Humans; Immune Sera; Immunoenzyme Techniques; Immunoglobulin G; Peroxidases; Sheep; Thyroxine

1995
Hapten-heterologous conjugates evaluated for application to free thyroxine immunoassays.
    Clinical chemistry, 1993, Volume: 39, Issue:2

    Topics: Animals; Antibodies; Antigens; Bacterial Proteins; Binding, Competitive; Biotin; Cattle; gamma-Globulins; Haptens; Humans; Immunoassay; Kinetics; Serum Albumin; Streptavidin; Thyroglobulin; Thyroxine; Triiodothyronine

1993
Clinical evaluation of biotin-binding immunoglobulin in patients with Graves' disease.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Volume: 226, Issue:1

    Topics: Adult; Amidohydrolases; Autoantibodies; Binding, Competitive; Biotin; Biotinidase; Carrier Proteins; Female; Graves Disease; Humans; Immunoenzyme Techniques; Immunoglobulins; Immunoglobulins, Thyroid-Stimulating; Male; Middle Aged; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine; Triiodothyronine

1994
Interference by biotin therapy on measurement of TSH and FT4 by enzyme immunoassay on Boehringer Mannheim ES700 analyser.
    Annals of clinical biochemistry, 1996, Volume: 33 ( Pt 2)

    Topics: Artifacts; Biotin; Female; Humans; Immunoenzyme Techniques; Infant, Newborn; Thyrotropin; Thyroxine

1996
Analytical application of host-guest chemistry using in vitro selection.
    Nucleic acids symposium series, 1997, Issue:37

    Topics: Antibodies; Base Sequence; Biological Assay; Biotin; DNA; Fluorescent Dyes; Folic Acid; Methotrexate; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Thyroxine

1997
Resin-supported labeling reagents.
    Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2

    Topics: Acridines; Biotin; Chromatography, High Pressure Liquid; Coumarins; Esters; Estriol; Fluorescein; Haptens; Phenytoin; Resins, Plant; Thyroxine

1999
Matrix interference in serum total thyroxin (T4) time-resolved fluorescence immunoassay (TRFIA) and its elimination with the use of streptavidin-biotin separation technique.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 308, Issue:1-2

    Topics: Antibodies, Monoclonal; Binding, Competitive; Biotin; Coated Materials, Biocompatible; Equipment Design; Fluoroimmunoassay; Humans; Immobilization; Immunoassay; Sensitivity and Specificity; Serum Albumin, Bovine; Streptavidin; Thyroxine

2001
Synthesis of hetero-telechelic alpha,omega bio-functionalized polymers.
    Biomacromolecules, 2010, Jan-11, Volume: 11, Issue:1

    Topics: Biotin; Magnetic Resonance Spectroscopy; Methacrylates; Polymers; Proteins; Streptavidin; Surface Plasmon Resonance; Thyroxine

2010
Regenerative electronic biosensors using supramolecular approaches.
    ACS nano, 2013, May-28, Volume: 7, Issue:5

    Topics: beta-Cyclodextrins; Biosensing Techniques; Biotin; Streptavidin; Thyroxine; Transistors, Electronic

2013
Interference from anti-streptavidin antibody.
    Archives of pathology & laboratory medicine, 2013, Volume: 137, Issue:8

    Topics: Antibodies, Heterophile; Biotin; Diagnostic Errors; Humans; Hyperthyroidism; Immunoassay; Immunosorbent Techniques; Male; Middle Aged; Sepharose; Streptavidin; Thyrotropin; Thyroxine

2013
Misdiagnosis of Graves' Disease with Apparent Severe Hyperthyroidism in a Patient Taking Biotin Megadoses.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:6

    Topics: Biotin; Diagnostic Errors; Dietary Supplements; Graves Disease; Humans; Hyperthyroidism; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine

2016
Immunoassay interference caused by heterophilic antibodies interacting with biotin.
    Clinical chemistry and laboratory medicine, 2017, May-01, Volume: 55, Issue:6

    Topics: Adult; Antibodies, Heterophile; Antithyroid Agents; Biomarkers; Biotin; False Positive Reactions; Humans; Hyperthyroidism; Immunoassay; Male; Methimazole; Thyrotropin; Thyroxine

2017
Consistent, but Totally Misleading, Thyroid Function Test Results.
    Clinical chemistry, 2017, Volume: 63, Issue:3

    Topics: Aged; Antibody Affinity; Biotin; False Positive Reactions; Humans; Hyperthyroidism; Immunoassay; Male; Multiple Sclerosis; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronine

2017
Ultrasensitive quantitative detection of small molecules with rapid lateral-flow assay based on high-affinity bifunctional ligand and magnetic nanolabels.
    Analytica chimica acta, 2018, Nov-30, Volume: 1034

    Topics: Antibodies, Monoclonal; Biotin; Chromatography, Affinity; Humans; Ligands; Magnetite Nanoparticles; Small Molecule Libraries; Thyroxine

2018
Biotin interference in TSH, FT4, and FT3 assays based on the LOCI technology: Identifying interference by dilution.
    Journal of clinical laboratory analysis, 2019, Volume: 33, Issue:2

    Topics: Biotin; Blood Chemical Analysis; Humans; Luminescent Measurements; Reproducibility of Results; Thyrotropin; Thyroxine; Triiodothyronine

2019
[Apparent thyrotoxicosis in a patient with multiple sclerosis: biochemical assay interference due to high dose biotin use].
    Nederlands tijdschrift voor geneeskunde, 2018, 02-14, Volume: 162

    Topics: Antithyroid Agents; Biotin; Diagnostic Errors; Female; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Male; Middle Aged; Multiple Sclerosis; Thyroid Function Tests; Thyrotoxicosis; Thyroxine

2018
Interferences in free thyroxine concentration using the Roche analytical platform: improvement of the third generation?
    Clinical chemistry and laboratory medicine, 2020, 01-28, Volume: 58, Issue:2

    Topics: Adult; Antibodies; Biotin; Female; Humans; Immunoassay; Reagent Kits, Diagnostic; Streptavidin; Thyroid Function Tests; Thyrotropin; Thyroxine

2020
Awareness of biotin: A growing problem in clinical practice.
    Endocrinologia, diabetes y nutricion, 2020, Volume: 67, Issue:1

    Topics: Autoantibodies; Autoantigens; Biotin; Diagnostic Errors; Female; Hashimoto Disease; Humans; Hyperthyroidism; Iodide Peroxidase; Iron-Binding Proteins; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Receptors, Thyrotropin; Streptavidin; Thyroid Function Tests; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine

2020
Comparison of Biotin Interference in Second- and Third-Generation Roche Free Thyroxine Immunoassays.
    Annals of laboratory medicine, 2020, Volume: 40, Issue:3

    Topics: Biotin; Humans; Immunoassay; Reagent Kits, Diagnostic; Thyroxine

2020
Assessment of biotin interference in thyroid function tests.
    Medicine, 2020, Volume: 99, Issue:9

    Topics: Administration, Oral; Adult; Biotin; Female; Healthy Volunteers; Humans; Male; Thyroid Function Tests; Thyroxine; Triiodothyronine; Vitamin B Complex; Young Adult

2020
When thyroid labs do not add up, physicians should ask patients about biotin supplements.
    BMJ case reports, 2020, Mar-31, Volume: 13, Issue:3

    Topics: Aged; Biotin; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Thyroid Function Tests; Thyrotropin; Thyroxine

2020
Biotin-induced thyroid stimulating hormone aberrations in the setting of immunotherapy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:8

    Topics: Aged; Biotin; Female; Humans; Immunotherapy; Thyroid Function Tests; Thyrotropin; Thyroxine

2021
Significant Interference of Biotin in Thyroid Function Tests Using Beckman Analyzer: How to Identify such Interferences?
    Annals of clinical and laboratory science, 2023, Volume: 53, Issue:1

    Topics: Biotin; Humans; Hyperthyroidism; Thyroglobulin; Thyroid Function Tests; Thyrotropin; Thyroxine

2023
Elevated free thyroxine and free triiodothyronine probably caused by high-dose biotin intake in a patient with Graves' disease: a case report.
    Endocrine journal, 2023, Aug-28, Volume: 70, Issue:8

    Topics: Biotin; Graves Disease; Humans; Male; Middle Aged; Streptavidin; Thyroid Hormones; Thyroxine; Triiodothyronine

2023